SynthesisJAMA facial plastic surgery2018
Masseteric Nerve Transfer for Facial Nerve Paralysis: A Systematic Review and Meta-analysis.
Synthesis in JAMA facial plastic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Facial nerve reconstruction for flaccid facial paralysis: a systematic review and meta-analysis.Frontiers in surgery · 2024Pooled it
- Comparison between VII-to-VII and XII-to-VII coaptation techniques for early facial nerve reanimation after surgical intra-cranial injuries: a systematic review and pooled analysis of the functional outcomes.Neurosurgical review · 2021Pooled it
- Clinical Studies and Pre-clinical Animal Models on Facial Nerve Preservation, Reconstruction, and Regeneration Following Cerebellopontine Angle Tumor Surgery-A Systematic Review and Future Perspectives.Frontiers in bioengineering and biotechnology · 2021Pooled it
- Acute Peripheral Facial Palsy: Recent Guidelines and a Systematic Review of the Literature.Journal of Korean medical science · 2020Pooled it
- A 25-Year Bibliometric and Scientometric Analysis of Facial Paralysis Rehabilitation: Knowledge Structure, Influential Works, and Emerging Research Frontiers (2000-2025).Microsurgery · 2026Article
- Optimizing facial reanimation: surgical landmarks for masseteric-to-facial nerve anastomosis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Postoperative Outcomes of Masseteric Nerve Transposition versus Cross-Facial Nerve Graft in Facial Reanimation: A Systematic Review and Meta-Analysis.Archives of plastic surgery · 2026Article
- Dual nerve transfer for postoperative facial paralysis: a 4-year clinical outcome report.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Single-Stage Versus 2-Stage Facial Reanimation With a Free Functional Muscle Flap: Protocol for a Systematic Review.JMIR research protocols · 2025Article
- Masseteric Nerve for Reanimation: Does Age, Radiation and Duration of Facial Palsy Affect the Outcome?Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- CONTEMPORARY CONCEPTS AND SURGICAL TECHNIQUES IN FACIAL REANIMATION: A SCOPING REVIEW.Acta clinica Croatica · 2025Article
- Free Vastus Lateralis Functional Muscle Transfer: An Approach to Facial Reanimation and Reconstruction in Radical Parotidectomy.Plastic and reconstructive surgery. Global open · 2025Article
- Masseteric-facial anastomosis and hypoglossal-facial anastomosis after lateral skull base and middle ear surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Novel Method of Dual-innervated Free Gracilis Muscle Transfer for Facial Reanimation: A Case Series.Plastic and reconstructive surgery. Global open · 2023Article
- Research trends and perspectives on immediate facial reanimation in radical parotidectomy (Review).Biomedical reports · 2023Review
- Anatomic Analysis of Masseteric-to-zygomatic Nerve Transfer in Rat and Pig Models.Plastic and reconstructive surgery. Global open · 2023Article
- Early Simultaneous Cross Facial Nerve Graft and Masseteric Nerve Transfer for Facial Paralysis after Tumor Resection.Plastic and reconstructive surgery. Global open · 2023Article
- Assessing the Efficacy of Anastomosis between Ansa Cervicalis and Facial Nerve for Patients with Concomitant Facial Palsy and Peripheral Neuropathy.Journal of personalized medicine · 2022Article
- Supercharging the Smile: A Novel Dual Nerve Transfer for Facial Reanimation.Plastic and reconstructive surgery. Global open · 2022Article
- The application of venous nerve conduit trap in the immediate repair and reconstruction of facial nerve in parotid gland tumor: an attempt of a new technique.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
importanceA review of the role of masseteric nerve transfer is needed to guide its use in facial reanimation.
objectiveTo systematically review the available literature, and, when applicable, analyze the combined outcomes of masseteric nerve transfer to better define its role in reanimation and to guide further research. DATA SOURCES: Two independent researchers conducted the review using PubMed-NCBI and Scopus literature databases for studies on masseteric nerve transfer for facial nerve paralysis. STUDY SELECTION: Studies that examined masseter nerve transfer with additional cranial nerve transposition/coaptation or muscle flap were excluded. DATA EXTRACTION AND SYNTHESIS: Literature review and data extraction followed established PRISMA guidelines. Two researchers extracted data independently. MAIN OUTCOMES AND MEASURES: The main planned outcomes for the study were quantitative results of facial nerve movement after nerve transfer including oral commissure movement and time to nerve recovery.
resultsA total of 13 articles met inclusion criteria with a total of 183 patients undergoing masseteric nerve transfer. From those studies, there were a total of 183 patients who underwent masseteric nerve transfer. There were 85 men and 98 women with a mean (SD) age of 43 (12.2) years and mean (SD) follow up examination after surgery of 22 (7.6) months. Mean (SD) duration of nerve paralysis was 14 (6) months. Most common cause of paralysis was cerebellopontine angle tumors (81%). Six studies coapted the masseteric nerve to the main facial nerve trunk, whereas 7 used distal branches (buccal or zygomatic). Four studies used interposition nerve grafts with great auricular nerve. Two measures, improvement in oral commissure excursion and length from reanimation to facial movement, were measured consistently across the studies. Pooled analysis showed time from surgery to first facial movement, described in 10 studies, to be 4.95 months (95% CI, 3.66 to 6.24). Distal branch coaptation improved time to recovery vs main branch coaptation, 3.76 vs 5.76 months (95% CI, -0.33 to 4.32), but mean difference was not significant. The use of interposition graft significantly delayed time of nerve recovery, 6.24 vs 4.06 months (95% CI, 0.20 to 4.16). When controlled for main trunk coaptation only, interposition nerve graft delayed recovery but difference was no longer statistically significant, 6.24 vs 4.75 months (95% CI, -0.94 to 3.92). Reported complications were minor and rare occurring in only 6.5% (12 of 183) of patients. CONCLUSIONS AND RELEVANCE: The masseteric nerve was found to be a good option for nerve transfer in this patient population, and showed favorable results in both time to nerve recovery and improvement in oral commissure excursion. LEVEL OF EVIDENCE: NA.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.