ArticleScientific reports2017
The Irish DNA Atlas: Revealing Fine-Scale Population Structure and History within Ireland.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Genetic ancestry and monogenic disease risk in the Scottish Traveller founder population.Nature communications · 2026Article
- The landscape of hereditary haemochromatosis risk and diagnosis across the British Isles and Ireland.Nature communications · 2026Article
- Genetic effects on migration behavior contribute to increasing spatial differentiation at trait-associated loci in Estonia.iScience · 2025Article
- The gut microbiome associated with LGI1-antibody encephalitis.Epilepsia · 2025Article
- Fine-scale regional frequency of theERJ open research · 2025Article
- A genetic perspective on the recent demographic history of Ireland and Britain.European journal of human genetics : EJHG · 2025Article
- Characterization of Y chromosome diversity in newfoundland and labrador: evidence for a structured founding population.European journal of human genetics : EJHG · 2025Article
- Human genetic structure in Northwest France provides new insights into West European historical demography.Nature communications · 2024Article
- Incidence and survival of uveal melanoma in Northern Ireland: how incomplete data can skew results in rare cancers.Eye (London, England) · 2023Article
- The Newfoundland and Labrador mosaic founder population descends from an Irish and British diaspora from 300 years ago.Communications biology · 2023Article
- Is there still evolution in the human population?Biologia futura · 2022Review
- Examining the source of increased bipolar disorder and major depressive disorder common risk variation burden in multiplex schizophrenia families.Schizophrenia (Heidelberg, Germany) · 2022Article
- Revealing the recent demographic history of Europe via haplotype sharing in the UK Biobank.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Why do we pick similar mates, or do we?Biology letters · 2021Review
- Fitness and Power: The Contribution of Genetics to the History of Differential Reproduction.Evolutionary psychology : an international journal of evolutionary approaches to psychology and behavior · 2021Article
- Changes in the fine-scale genetic structure of Finland through the 20th century.PLoS genetics · 2021Article
- Human Genomic Diversity Where the Mediterranean Joins the Atlantic.Molecular biology and evolution · 2020Article
- The future of genomics in Ireland - focus on genomics for health.HRB open research · 2020Article
- The genetic landscape of Scotland and the Isles.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
Abstract
The extent of population structure within Ireland is largely unknown, as is the impact of historical migrations. Here we illustrate fine-scale genetic structure across Ireland that follows geographic boundaries and present evidence of admixture events into Ireland. Utilising the 'Irish DNA Atlas', a cohort (n = 194) of Irish individuals with four generations of ancestry linked to specific regions in Ireland, in combination with 2,039 individuals from the Peoples of the British Isles dataset, we show that the Irish population can be divided in 10 distinct geographically stratified genetic clusters; seven of 'Gaelic' Irish ancestry, and three of shared Irish-British ancestry. In addition we observe a major genetic barrier to the north of Ireland in Ulster. Using a reference of 6,760 European individuals and two ancient Irish genomes, we demonstrate high levels of North-West French-like and West Norwegian-like ancestry within Ireland. We show that that our 'Gaelic' Irish clusters present homogenous levels of ancient Irish ancestries. We additionally detect admixture events that provide evidence of Norse-Viking gene flow into Ireland, and reflect the Ulster Plantations. Our work informs both on Irish history, as well as the study of Mendelian and complex disease genetics involving populations of Irish ancestry.
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