ReviewHematology. American Society of Hematology. Education Program2017
Symptomatic subsegmental pulmonary embolism: to treat or not to treat?
Review in Hematology. American Society of Hematology. Education Program, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Ruling out pulmonary embolism across different healthcare settings: A systematic review and individual patient data meta-analysis.PLoS medicine · 2022Pooled it
- Deep learning-based algorithm for automatic detection of incidental pulmonary embolism on contrast-enhanced CT: a multicenter multivendor study.Radiology advances · 2025Article
- Article
- Exploring varied radiologic appearance in pulmonary embolism with CT pulmonary angiography: Case series with literature review.Radiology case reports · 2024Article
- The History of Diagnosing Venous Thromboembolism.Seminars in thrombosis and hemostasis · 2024Review
- Augmentation of the RSNA Pulmonary Embolism CT Dataset with Bounding Box Annotations and Anatomic Localization of Pulmonary Emboli.Radiology. Artificial intelligence · 2023Article
- Anticoagulation strategy and safety in critically ill COVID-19 patients: a French retrospective multicentre study.Thrombosis journal · 2023Article
- Deep Learning-Based Algorithm for Automatic Detection of Pulmonary Embolism in Chest CT Angiograms.Diagnostics (Basel, Switzerland) · 2023Article
- How to Combat Over-Testing for Patients Suspected of Pulmonary Embolism: A Narrative Review.Diagnostics (Basel, Switzerland) · 2023Review
- Clinical Significance and Outcome in Patients with Asymptomatic Versus Symptomatic Subsegmental Pulmonary Embolism.Journal of clinical medicine · 2023Article
- A multicentre observational study of the prevalence, management, and outcomes of subsegmental pulmonary embolism.Journal of thrombosis and thrombolysis · 2023Observational
- Article
- Diagnostic Management of Acute Pulmonary Embolism in COVID-19 and Other Special Patient Populations.Diagnostics (Basel, Switzerland) · 2022Review
- Pulmonary embolism severity and in-hospital mortality: An international comparative study between COVID-19 and non-COVID patients.European journal of internal medicine · 2022Article
- Article
- Can clot size and stenotic degree predict perfusion defects on conventional computed tomographic pulmonary angiography in diagnoses of pulmonary embolism?Polish journal of radiology · 2022Article
- Tranexamic acid administration and pulmonary embolism in combat casualties with orthopaedic injuries.OTA international : the open access journal of orthopaedic trauma · 2021Article
- Incidence of thrombotic complications and overall survival in hospitalized patients with COVID-19 in the second and first wave.Thrombosis research · 2021Article
- Article
- Establishing diagnostic criteria and treatment of subsegmental pulmonary embolism: A Delphi analysis of experts.Research and practice in thrombosis and haemostasis · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The introduction of computed tomographic pulmonary angiography and its recent increasing availability has led to a significant rise in its use to help clinicians diagnose acute pulmonary embolism (PE). This has led to a significant increase in the incidence of PE diagnoses. Simultaneously, the case fatality rate of acute PE has been decreasing and no significant change in its mortality has been noted, suggesting that the additional PE diagnoses are less severe and these patients might not benefit from anticoagulation therapy. This also seems to be correlated with an increase in the diagnosis of PE localized in the subsegmental pulmonary arteries (subsegmental pulmonary embolism [SSPE]). The clinical importance of SSPE is unclear. Whereas some studies have shown that it might be reasonable to manage patients with SSPE without anticoagulation, others have not. Although the current medical literature is limited, it suggests that a subgroup of patients with SSPE might be safely managed without the use of anticoagulant therapy. Current clinical practice guidelines suggest that clinicians take an individualized approach after carefully assessing the risk/benefit ratio for patients with SSPE and negative leg limb ultrasonography results. Prospective studies are ongoing and results are eagerly awaited to help tailor the management of this patient population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.