Evidence map›Paper›PMID 29222176›Full record

ArticleThe EMBO journal2018

Ca

Xin Bian, Yasunori Saheki, Pietro De Camilli

Open access · bronzeAbstract read
In one paragraph

Article in The EMBO journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 144 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. CaBMC biology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Extended Synaptotagmins ofPlants (Basel, Switzerland) · 2025
    Review
  13. DNA-Assisted Assays for Studying Lipid Transfer Between Membranes.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  14. Cowpea lipid transfer protein 1 regulates plant defense by inhibiting the cysteine protease of cowpea mosaic virus.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Xin BianDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-5501-0471
Yasunori SahekiDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT, USA yasunori.saheki@ntu.edu.sg pietro.decamilli@yale.edu.ORCID 0000-0002-1229-6668
Pietro De CamilliDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT, USA yasunori.saheki@ntu.edu.sg pietro.decamilli@yale.edu.ORCID 0000-0001-9045-0723
Howard Hughes Medical Institute · US

Funding

Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Richard A Flavell · 1993 to 2026
$44.0M
Yale/NIDA Neuroproteomics Research CenterP30DA018343 · NIDA · YALE UNIVERSITY · PI Marina R Picciotto · 2004 to 2026
$37.1M
MOLECULAR MECHANISMS IN SYNAPTIC VESICLE RECYCLINGR01NS036251 · NINDS · YALE UNIVERSITY · PI DE CAMILLI, PIETRO · 1997 to 2021
$4.7M
Molecular Mechanisms in Synaptic Vesicle RecyclingR37NS036251 · NINDS · YALE UNIVERSITY · PI DE CAMILLI, PIETRO · 2010 to 2016
$2.7M
NIDA NIH HHS P30 DA018343NIDDK NIH HHS P30 DK045735NINDS NIH HHS R01 NS036251NINDS NIH HHS R37 NS036251
6 · The paper itself

Abstract

The extended synaptotagmins (E-Syts) are endoplasmic reticulum (ER) proteins that bind the plasma membrane (PM) via C2 domains and transport lipids between them via SMP domains. E-Syt1 tethers and transports lipids in a Ca

Indexed as

Biological Transport, ActiveCalciumCalcium SignalingCell LineCell MembraneEndoplasmic ReticulumHumansLipid MetabolismPhosphatidylinositol 4,5-DiphosphateProtein DomainsSynaptotagminsCalciumESYT1 protein, humanPhosphatidylinositol 4,5-DiphosphateSynaptotagminsC2 domainextended synaptotagminlipid transferphosphatidylserine scramblingSMP domain

Identifiers

PMID29222176
PMCPMC5770786
OpenAlexW2775171921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.