Evidence map›Paper›PMID 29222175›Full record

ArticleBiology open2018

Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis.

Assunta Liberti, Ivana Zucchetti, Daniela Melillo, Diana Skapura, Yoshimi Shibata, Rosaria De Santis, Maria Rosaria Pinto, Gary W Litman, Larry J Dishaw

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Tethering of soluble immune effectors to mucin and chitin reflects a convergent and dynamic role in gut immunity.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Assunta LibertiDepartment of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy ldishaw@health.usf.edu libertia@mail.usf.edu.ORCID http://orcid.org/0000-0001-9097-2871
Ivana ZucchettiDepartment of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy.
Daniela MelilloDepartment of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy.
Diana SkapuraMolecular Genetics, Johns Hopkins All Children's Hospital, Saint Petersburg, FL 33701, USA.
Yoshimi ShibataBiomedical Science Department, Florida Atlantic University, Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA.
Rosaria De SantisDepartment of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy.
Maria Rosaria PintoDepartment of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy.
Gary W LitmanUniversity of South Florida, Morsani College of Medicine, Department of Pediatrics, Tampa, FL 33606, USA.
Larry J DishawUniversity of South Florida, Morsani College of Medicine, Department of Pediatrics, Tampa, FL 33606, USA ldishaw@health.usf.edu libertia@mail.usf.edu.ORCID http://orcid.org/0000-0002-2705-4573
Stazione Zoologica Anton Dohrn · ITUniversity of South Florida · USFlorida Atlantic University · USJohns Hopkins University · US

Funding

EVOLUTIONARY ORIGINS OF IMMUNE-TYPE GENESR01AI023338 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI LITMAN, GARY WILLIAM · 1985 to 2014
$3.6M
EARLY EVOLUTIONARY ORIGINS OF IMMUNOGLOBULIN GENESR37AI023338 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI LITMAN, GARY W · 1995 to 2003
$1.6M
Dietary anti-inflammatory chitin in colitisR15AT008252 · NCCIH · FLORIDA ATLANTIC UNIVERSITY · PI SHIBATA, YOSHIMI · 2014 to 2014
$381k
Evolutionary Origins of Immune-Type GenesR56AI023338 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI LITMAN, GARY WILLIAM · 2009 to 2009
$77k
NCCIH NIH HHS R15 AT008252NIAID NIH HHS R01 AI023338NIAID NIH HHS R37 AI023338NIAID NIH HHS R56 AI023338
6 · The paper itself

Abstract

The gastrointestinal tract of

Indexed as

Chitin-rich mucusCiona intestinalisDSS-induced colitisHost-microbes interactionInflammatory bowel diseaseVCBPs

Identifiers

PMID29222175
PMCPMC5827265
OpenAlexW2772341970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.