ReviewAdvanced drug delivery reviews2018
Drug delivery and tissue engineering to promote wound healing in the immunocompromised host: Current challenges and future directions.
Review in Advanced drug delivery reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Skin organoid transplantation promotes tissue repair with scarless in frostbite.Protein & cell · 2025Article
- Dual-layer microneedles with NO/OBioactive materials · 2025Article
- The landscape of biofilm models for phage therapy: mimicking biofilms in diabetic foot ulcers using 3D models.Frontiers in microbiology · 2025Review
- Skin repair and infection control in diabetic, obese mice using bioactive laser-activated sealants.Biomaterials · 2024Article
- Reconstructive Surgery of the Head and Neck in Organ Transplant Recipients: A Case Report and a Review of the Literature.Journal of clinical medicine · 2024Review
- Surface Modification Progress for PLGA-Based Cell Scaffolds.Polymers · 2024Review
- Discussing the final size and shape of the reconstructed tissues in tissue engineering.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2023Review
- Surface-Active Compounds Produced by Microorganisms: Promising Molecules for the Development of Antimicrobial, Anti-Inflammatory, and Healing Agents.Antibiotics (Basel, Switzerland) · 2022Review
- Porous Se@SiOFrontiers in bioengineering and biotechnology · 2022Article
- Tobramycin Supplemented Small-Diameter Vascular Grafts for Local Antibiotic Delivery: A Preliminary Formulation Study.International journal of molecular sciences · 2021Article
- Nano-in-Micro Dual Delivery Platform for Chronic Wound Healing Applications.Micromachines · 2020Article
- A murine model of cutaneous aspergillosis for evaluation of biomaterials-based local delivery therapies.Journal of biomedical materials research. Part A · 2019Article
- Tannic Acid Accelerates Cutaneous Wound Healing in Rats Via Activation of theAdvances in wound care · 2019Article
- Physicochemical and Biocompatibility Properties of Type I Collagen from the Skin of Nile Tilapia (Marine drugs · 2019Article
- Capsule-Integrated Polypeptide Multilayer Films for Effective pH-Responsive Multiple Drug Co-Delivery.ACS applied materials & interfaces · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
As regenerative medicine matures as a field, more promising technologies are being translated from the benchtop to the clinic. However, many of these strategies are designed with otherwise healthy hosts in mind and validated in animal models without other co-morbidities. In reality, many of the patient populations benefiting from drug delivery and tissue engineering-based devices to enhance wound healing also have significant underlying immunodeficiency. Specifically, patients suffering from diabetes, malignancy, human immunodeficiency virus, post-organ transplantation, and other compromised states have significant pleotropic immune defects that affect wound healing. In this work, we review the role of different immune cells in the regenerative process, highlight the effect of several common immunocompromised states on wound healing, and discuss different drug delivery strategies for overcoming immunodeficiencies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.