Evidence map›Paper›PMID 29221919›Full record

ReviewThe journal of allergy and clinical immunology. In practice

Impact of Lifestyle Interventions Targeting Healthy Diet, Physical Activity, and Weight Loss on Asthma in Adults: What Is the Evidence?

Sharmilee M Nyenhuis, Anne E Dixon, Jun Ma

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05726487 (ACTION), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05726487 naactive not recruitingnot on this map

ACTION (physicAl aCtiviTy In minOrity womeN With Asthma) Intervention: Efficacy to Implementation

TypeinterventionalSponsorUniversity of ChicagoRan2023 to 2026Enrolled224ConditionsAsthmaArmsACTION Intervention, Education Control
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. A Systematic Review of the Effect of Physical Activity on Asthma Outcomes.The journal of allergy and clinical immunology. In practice · 2021
    Pooled it
  2. Trial
  3. Article
  4. The Role of Lipid Metabolism Disorders in Rhinitis and Asthma.Combinatorial chemistry & high throughput screening · 2026
    Review
  5. Article
  6. Article
  7. The Circadian Rhythm of Asthma Immune Metabolism.Journal of immunology research · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. The Association of Food Insecurity With Asthma Control in Adults During COVID-19.The journal of allergy and clinical immunology. In practice · 2023
    Article
  17. Relationship Between Physical Activity and Adult Asthma Control Using NHANES 2011-2020 Data.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sharmilee M NyenhuisDivision of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Ill. Electronic address: snyenhui@uic.edu.
Anne E DixonDepartment of Medicine, Pulmonary and Critical Care Medicine, University of Vermont, Burlington, Vt.
Jun MaDepartment of Health Policy and Administration, Institute of Health Research and Policy, University of Illinois at Chicago, Chicago, Ill.
University of Illinois Chicago · USUniversity of Vermont · US

Funding

Obese Allergic Asthma and the Impact of Weight Loss on Airway Epithelial FunctionR01HL133920 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI DIXON, ANNE E, POYNTER, MATTHEW E · 2016 to 2020
$3.9M
Non-Allergic Late-Onset Asthma of Obesity: Pathophysiology and TherapyR01HL130847 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BATES, JASON HT, DIXON, ANNE E · 2016 to 2019
$2.3M
Ketone Body Supplementation in Obese AsthmaR01HL142081 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI POYNTER, MATTHEW E · 2018 to 2021
$1.8M
Health through Obesity care for PatiEnts with COPD (HOPE)U01HL128868 · NHLBI · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI AU, DAVID H, MA, JUN · 2015 to 2018
$1.2M
ACTION Intervention: Physical Activity in Minority Women with AsthmaK01HL133370 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI NYENHUIS, SHARMILEE MARIA · 2016 to 2019
$741k
NHLBI NIH HHS K01 HL133370NHLBI NIH HHS R01 HL130847NHLBI NIH HHS R01 HL133920NHLBI NIH HHS R01 HL142081NHLBI NIH HHS U01 HL128868
6 · The paper itself

Abstract

Unhealthy lifestyle factors such as poor diet quality, sedentary lifestyle, and obesity are associated with negative health consequences in asthma including poor asthma control, impaired quality of life, and greater health care utilization. Lifestyle modification is the cornerstone of behavioral treatments and has been effective in chronic diseases such as atherothrombotic vascular disease and diabetes. There is a critical need for lifestyle interventions in asthma care that address obesity and its intimately linked risk behaviors in terms of poor diet and physical inactivity. We present in this commentary the promising lifestyle interventions emerging in asthma care that target poor diet, physical inactivity and weight loss, the proposed mechanisms of these lifestyle interventions, and the critical need for guideline-concordant lifestyle interventions in asthma care.

Indexed as

AdultAsthmaDiet, HealthyExerciseHumansLife StyleWeight LossAsthmaDietObesityPhysical activityWeight loss

Identifiers

PMID29221919
PMCPMC5948112
OpenAlexW2775350253

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.