Evidence map›Paper›PMID 29221439›Full record

ArticleBMC nephrology2017

Catheter-related blood stream infections in hemodialysis patients: a prospective cohort study.

Stephanie Thompson, Natasha Wiebe, Scott Klarenbach, Rick Pelletier, Brenda R Hemmelgarn, John S Gill, Braden J Manns, Marcello Tonelli, Alberta Kidney Disease Network

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Epidemiology of haemodialysis outcomes.Nature reviews. Nephrology · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Stephanie ThompsonDivision of Nephrology and Immunology 11-112 CSB, 152 University Campus NW, University of Alberta, Edmonton, AB, T6G 2G3, Canada.
Natasha WiebeDivision of Nephrology and Immunology 11-112 CSB, 152 University Campus NW, University of Alberta, Edmonton, AB, T6G 2G3, Canada.
Scott KlarenbachDivision of Nephrology and Immunology 11-112 CSB, 152 University Campus NW, University of Alberta, Edmonton, AB, T6G 2G3, Canada.
Rick PelletierDepartment of Renewable Resources, Faculty of Agriculture, Life and Environmental Sciences, University of Alberta, 442 Earth Sciences Building, Edmonton, AB, T6G 2E3, Canada.
Brenda R HemmelgarnDivision of Nephrology, University of Calgary, Foothills Medical Centre, 1403-29th Street NW, Calgary, AB, T2N 2T9, Canada.
John S GillDivision of Nephrology and Centre for Health Evaluation and Outcome Sciences, University of British Columbia, BC 1081 Burrard Street Vancouver, Vancouver, BC, V6Z 1Y6, Canada.
Braden J MannsDivision of Nephrology, University of Calgary, Foothills Medical Centre, 1403-29th Street NW, Calgary, AB, T2N 2T9, Canada.
Marcello TonelliDepartment of Medicine, University of Calgary, 7th Floor, TRW Building, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada. cello@ucalgary.ca.ORCID http://orcid.org/0000-0002-0846-3187
Alberta Kidney Disease Network
University of Alberta · CAUniversity of British Columbia · CAUniversity of Calgary · CA

Funding

Canadian Institutes of Health Research MOP-74459
6 · The paper itself

Abstract

backgroundFor people requiring hemodialysis, infectious mortality is independently associated with geographic distance from a nephrologist. We aimed to determine if differential management of catheter-related blood stream infections (CRBSIs) could explain poorer outcomes.

methodsWe prospectively collected data from adults initiating hemodialysis with a central venous catheter between 2005 and 2015 in Alberta, Canada. We collected indicators of CRBSI management (timely catheter removal, relapsing bacteremia); frequency of CRBSIs; hospitalizations; predictors of CRBSIs, and bacteremia. We evaluated indicators and infectious episodes as a function of the shortest distance by road to the closest nephrologist's practice: <50 (referent); 50-99; and ≥100 km.

resultsOne thousand one hundred thirty-one participants were followed for a median of 755 days (interquartile range (IQR) 219, 1465) and used dialysis catheters for a median of 565 days (IQR 176, 1288). Compared to the referent group, there was no significant difference in the rate ratio (RR) of CRBSI in the 50-100 and >100 km distance categories: RR 1.63; 95% confidence interval (CI) (0.91, 2.91); RR 0.84 (95% CI 0.44, 1.58); p = 0.87, respectively or in bacteremia: RR 1.42; (95% CI 0.83, 2.45); RR 0.79 (95% CI 0.45,1.39) p = 0.74, respectively. There were no differences in indicators of appropriate CRBSI management or hospitalizations according to distance. The overall incidence of CRBSIs was low (0.19 per 1000 catheter days) as was the frequency of relapse. Only liver disease was independently associated with CRBSI (RR 2.11; 95% CI 1.15, 3.86).

conclusionsThe frequency and management of CRBSIs did not differ by location; however, event rates were low.

Indexed as

Catheter-Related InfectionsKidney Failure, ChronicNephrologistsPatient Care ManagementRenal DialysisAdultAgedBacteremiaCanadaCentral Venous CathetersDevice RemovalFemaleHealth Services AccessibilityHumansIncidenceMaleBacteremiaCatheterHemodialysisResidence location

Identifiers

PMID29221439
PMCPMC5723103
OpenAlexW2773159536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.