ArticleJournal of thoracic disease2017
AB thymoma with atypical type A component with delayed multiple lung and brain metastases.
Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Distinct Associations ofGenes · 2026Article
- Atypical type A thymoma: a narrative review of a distinct and progressive variant of low-risk thymoma.Mediastinum (Hong Kong, China) · 2026Review
- Clinico-pathologic study of 252 resected thymomas with emphasis on atypical A and AB group: a single institution experience.Mediastinum (Hong Kong, China) · 2025Article
- Rare atypical type a thymoma: a case report and literature review.Diagnostic pathology · 2024Review
- Differences and similarities ofTranslational lung cancer research · 2023Article
- Atypical type A thymoma component identified by pulmonary metastasectomy 11 years after surgery of type AB thymoma.Respiratory medicine case reports · 2023Article
- Fibrous bands associated with higher Masaoka stage and poor recurrence-free survival in patients with thymoma.Thoracic cancer · 2021Article
- Mutant GTF2I induces cell transformation and metabolic alterations in thymic epithelial cells.Cell death and differentiation · 2020Article
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An atypical type A thymoma is a newly added entity to the last World Health Organization (WHO) histological classification [2015] of uncertain prognosis. The conventional type A and AB thymomas are usually locally aggressive neoplasms that rarely metastasize with distant metastases to the central nervous system (CNS) occurring extremely exceptionally. We present a history of a woman with a mediastinal tumor originally considered to be a Masaoka-Koga stage II "mixed thymoma with well-differentiated thymic carcinoma component" according to the historic Müller-Hermelink nomenclature. By applying the criteria of the new WHO classification the tumor should be reclassified as an AB thymoma with an atypical A component. The patient developed metastases to the lung and brain 10 and 15 years after the original diagnosis, respectively. All metastases morphologically corresponded to an atypical A component of primary thymoma. Molecular study revealed
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