ArticleJournal of thoracic disease2017
A comparative study of conventional cytology and cell block method in the diagnosis of pleural effusion.
Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Sensitivity and complications of thoracentesis and thoracoscopy: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Development and validation of a novel scoring system developed from a nomogram to identify malignant pleural effusion.EBioMedicine · 2020Trial
- A Study Investigating Markers in PLeural Effusion (SIMPLE): a prospective and double-blind diagnostic study.BMJ open · 2019Trial
- Derivation and validation of a clinical prediction model incorporating the pleural fluid ADA-to-LDH ratio for differentiating tuberculous from malignant pleural effusions: a multi-center study.BMC pulmonary medicine · 2026Article
- Article
- Investigation of the Prevalence of Chronic Pulmonary Effusion Causes and Response to Treatment (Pleurodesis) in Patients.The open respiratory medicine journal · 2025Article
- Malignant Pleural Effusion: Diagnosis and Treatment-Up-to-Date Perspective.Current oncology (Toronto, Ont.) · 2024Review
- A comparative diagnostic yield among cytologic examination, cell block and closed pleural biopsy in exudative pleural effusion.Journal of thoracic disease · 2024Article
- Beyond diagnosis: a narrative review of the evolving therapeutic role of medical thoracoscopy in the management of pleural diseases.Journal of thoracic disease · 2024Review
- Enhancing diagnostic precision in thyroid nodule assessment: evaluating the efficacy of a novel cell preservation technique in fine-needle aspiration cytology.Frontiers in endocrinology · 2024Article
- Diagnostic analysis of pleural fluid cell blocks using relevant immunohistochemical markers in clinically suspicious cases of malignancy.CytoJournal · 2024Article
- Handling and standardization of EBUS needle aspiration in NSCLC patients: The value of the cell block, a monoinstitutional experience.Thoracic cancer · 2022Article
- Echogenic swirling pattern, carcinoembryonic antigen, and lactate dehydrogenase in the diagnosis of malignant pleural effusion.Scientific reports · 2022Article
- ALDH1 and SALL4 Expression in Cell Block Samples from Patients with Lung Adenocarcinoma and Malignant Pleural Effusion.Diagnostics (Basel, Switzerland) · 2021Article
- Article
- Development and Validation of a Scoring System for Early Diagnosis of Malignant Pleural Effusion Based on a Nomogram.Frontiers in oncology · 2021Article
- Role of cancer ratio and other new parameters in the differential diagnosis of malignant pleural effusion.Clinics (Sao Paulo, Brazil) · 2021Article
- Architectural aspects of cell-blocks as small biopsies.CytoJournal · 2021Review
- Diagnosis of Hodgkin Lymphoma from Cell Block: A Reliable and Helpful Tool in "Selected" Diagnostic Practice.Diagnostics (Basel, Switzerland) · 2020Article
- Diagnostic accuracy of cancer ratio for malignant pleural effusion: a systematic review and meta-analysis.Annals of translational medicine · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn a patient with pleural effusion, cytological study (CS) is one of the most useful investigations, especially when malignancy is suspected. Instead of applying only CS, the pleural fluid can be further processed using the cell block (CB) technique, which may augment the diagnostic utility. The aim of this study was to compare the diagnostic yields of CS, CB, and the combination of both, regardless of the etiology of pleural effusion.
methodsA cross-sectional study was conducted on patients with pleural effusions who underwent thoracentesis from June 2015 to May 2016. All samples were submitted for routine biochemical analysis, CS, and CB histology. The results of cytopathological studies were compared to the final diagnoses.
resultsOut of a total of 353 samples, the final diagnoses included 278 (78.8%) malignancies, 41 (11.6%) infectious diseases, 16 (4.5%) other inflammatory diseases, and 18 (5.1%) transudative pleural effusions. CS and CB provided a similar diagnostic yield (48.7%
conclusionsIn MPE, CB provides a similar diagnostic performance to CS, while application of both techniques can significantly increase the diagnostic yield. However, in other pleural diseases, CB and CS had limited values in diagnosis.
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