Evidence map›Paper›PMID 29221286›Full record

ArticleJournal of thoracic disease2017

Automatic Lung-RADS™ classification with a natural language processing system.

Sebastian E Beyer, Brady J McKee, Shawn M Regis, Andrea B McKee, Sebastian Flacke, Gilan El Saadawi, Christoph Wald

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sebastian E BeyerDepartment of Radiology, Lahey Hospital and Medical Center, Burlington, MA, USA.
Brady J McKeeDepartment of Radiology, Lahey Hospital and Medical Center, Burlington, MA, USA.
Shawn M RegisDepartment of Radiation Oncology, Lahey Hospital and Medical Center, Burlington, MA, USA.
Andrea B McKeeDepartment of Radiation Oncology, Lahey Hospital and Medical Center, Burlington, MA, USA.
Sebastian FlackeDepartment of Radiology, Lahey Hospital and Medical Center, Burlington, MA, USA.
Gilan El SaadawiCMIO at MModal, Imaging Solutions, Pittsburgh, PA, USA.
Christoph WaldDepartment of Radiology, Lahey Hospital and Medical Center, Burlington, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur aim was to train a natural language processing (NLP) algorithm to capture imaging characteristics of lung nodules reported in a structured CT report and suggest the applicable Lung-RADS™ (LR) category.

methodsOur study included structured, clinical reports of consecutive CT lung screening (CTLS) exams performed from 08/2014 to 08/2015 at an ACR accredited Lung Cancer Screening Center. All patients screened were at high-risk for lung cancer according to the NCCN Guidelines

resultsThe sensitivity/specificity of the NLP algorithm to correctly assign LR categories for suspicious nodules (LR 4) and positive nodules (LR 3/4) were 74.1%/98.6% and 75.0%/98.8% respectively. The majority of mismatches occurred in cases where pulmonary findings were present not currently addressed by LR. Misclassifications also resulted from the failure to identify exams as follow-up and the failure to completely characterize part-solid nodules. In a sub-group analysis among structured reports with standardized language, the sensitivity and specificity to detect LR 4 nodules were 87.0% and 99.5%, respectively.

conclusionsAn NLP system can accurately suggest the appropriate LR category from CTLS exam findings when standardized reporting is used.

Indexed as

CT lung screening (CTLS)Lung-RADS™ (LR)natural language processing (NLP)

Identifiers

PMID29221286
PMCPMC5708435

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.