Evidence map›Paper›PMID 29221272›Full record

ArticleJournal of thoracic disease2017

Goal-directed fluid restriction using stroke volume variation and cardiac index during one-lung ventilation: a randomized controlled trial.

Hui Xu, Shu-Hua Shu, Di Wang, Xiao-Qing Chai, Yan-Hu Xie, Wei-De Zhou

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04209218 (Impact of Intraoperative Blood Pressure Management and Dexamethasone on Patient's Outcomes After Lung Cancer Surgery), which is not on this map. Cited by 22 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 7 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04209218 narecruitingnot on this mapstarted 2020, after this paper: background citation

Impact of Intraoperative Blood Pressure Management and Dexamethasone on Patient's Outcomes After Lung Cancer Surgery: A 2 × 2 Factorial Randomized Controlled Trial

TypeinterventionalSponsorPeking University First HospitalRan2020 to 2029Enrolled1,988ConditionsLung Cancer, Surgery, Blood Pressure Management, DexamethasoneArmsDexamethasone, Targeted blood pressure management, Placebo, Routine blood presure management
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 7 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hui XuDepartment of Anesthesiology, Anhui Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Shu-Hua ShuDepartment of Anesthesiology, Anhui Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Di WangDepartment of Anesthesiology, Anhui Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Xiao-Qing ChaiDepartment of Anesthesiology, Anhui Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Yan-Hu XieDepartment of Anesthesiology, Anhui Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Wei-De ZhouDepartment of Anesthesiology, Anhui Provincial Hospital, Anhui Medical University, Hefei 230001, China.
Anhui Medical University · CNAnhui Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGoal-directed therapy confers a strong prognosis in patients undergoing major cardiac or noncardiac surgery. The present study investigated whether intraoperative goal-directed fluid restriction (GDFR) using stroke volume variation (SVV) and cardiac index could improve oxygenation and postoperative outcome in patients undergoing one-lung ventilation (OLV).

methodsA Total of 168 patients scheduled for elective thoracoscopic lobectomy under OLV were randomized into the GDFR protocol (group G) or conventional fluid therapy groups (group C). Patients in group C underwent conventional fluid therapy based on mean arterial pressure (MAP), central venous pressure (CVP), and urine volume, whereas those in group G received GDFR protocol associated with the SVV from 10-13% and the cardiac index was controlled at a minimum of 2.5 L/min/m

resultsDuring surgery, the PaO

conclusionsThe GDFR protocol based on SVV and cardiac index applied in patients undergoing OLV improves intraoperative pulmonary oxygenation. It can also reduce the postoperative complications and length of hospital stay. However, the GDFR strategy cannot reduce the local or systemic inflammation.

trial registrationChinese Clinical Trials Register ChiCTR-INR-16008288, Registered 20 April, 2016.

Indexed as

Fluid therapylung functionone-lung ventilation (OLV)stroke volume variation (SVV)

Identifiers

PMID29221272
PMCPMC5708410
OpenAlexW2753432964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.