Evidence map›Paper›PMID 29221175›Full record

ArticleOncotarget2017

TRPM8 is required for survival and radioresistance of glioblastoma cells.

Dominik Klumpp, Stephanie C Frank, Lukas Klumpp, Efe C Sezgin, Marita Eckert, Lena Edalat, Martin Bastmeyer, Daniel Zips, Peter Ruth, Stephan M Huber

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Roles of TRPM channels in glioma.Cancer biology & therapy · 2024
    Review
  3. Review
  4. Ion Channels in Gliomas-From Molecular Basis to Treatment.International journal of molecular sciences · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. Ion Transport and Radioresistance.Reviews of physiology, biochemistry and pharmacology · 2022
    Review
  9. Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges.Reviews of physiology, biochemistry and pharmacology · 2022
    Review
  10. Article
  11. Review
  12. Article
  13. TRP Channels in Brain Tumors.Frontiers in cell and developmental biology · 2021
    Review
  14. Ion Channels in Glioma Malignancy.Reviews of physiology, biochemistry and pharmacology · 2021
    Review
  15. Potassium Channels in Cancer.Handbook of experimental pharmacology · 2021
    Article
  16. Review
  17. Review
  18. Review
  19. CaAdvances in cancer research · 2020
    Review
  20. hERG KFrontiers in pharmacology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Dominik KlumppDepartment of Radiation Oncology, University of Tübingen, Tübingen, Germany.
Stephanie C FrankZoological Institute, Department of Cell- and Neurobiology, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Lukas KlumppDepartment of Radiation Oncology, University of Tübingen, Tübingen, Germany.
Efe C SezginDepartment of Radiation Oncology, University of Tübingen, Tübingen, Germany.
Marita EckertDepartment of Radiation Oncology, University of Tübingen, Tübingen, Germany.
Lena EdalatDepartment of Radiation Oncology, University of Tübingen, Tübingen, Germany.
Martin BastmeyerZoological Institute, Department of Cell- and Neurobiology, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Daniel ZipsDepartment of Radiation Oncology, University of Tübingen, Tübingen, Germany.
Peter RuthDepartment of Pharmacology, Toxicology and Clinical Pharmacy, University of Tübingen, Tübingen, Germany.
Stephan M HuberDepartment of Radiation Oncology, University of Tübingen, Tübingen, Germany.
University of Tübingen · DEKarlsruhe Institute of Technology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TRPM8 is a Ca

Indexed as

Ca2+ signalingcell migrationglioblastomaradioresistanceTRPM8 channels

Identifiers

PMID29221175
PMCPMC5707069
OpenAlexW2758710783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.