Evidence map›Paper›PMID 29221136›Full record

ArticleOncotarget2017

Raffaella Cascella, Claudia Strafella, Michele Ragazzo, Laura Manzo, Gaetana Costanza, John Bowes, Ulrike Hüffmeier, Saverio Potenza, Federica Sangiuolo, André Reis and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. RNAseq-Based Prioritization RevealedInternational journal of molecular sciences · 2020
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Raffaella Cascella *Molecular Genetics Laboratory UILDM, Santa Lucia Foundation, Rome, Italy.
Claudia Strafella *Department of Biomedicine and Prevention, "Tor Vergata" University, Rome, Italy.
Michele RagazzoMolecular Genetics Laboratory UILDM, Santa Lucia Foundation, Rome, Italy.
Laura ManzoDepartment of Biomedicine and Prevention, "Tor Vergata" University, Rome, Italy.
Gaetana CostanzaAnatomic Pathology, Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
John BowesArthritis Research UK Centre for Genetics and Genomics, The University of Manchester, Manchester, UK.
Ulrike HüffmeierInstitute of Human Genetics, University of Erlangen-Nuremberg, Erlangen, Germany.
Saverio PotenzaDepartment of Biomedicine and Prevention, "Tor Vergata" University, Rome, Italy.
Federica SangiuoloDepartment of Biomedicine and Prevention, "Tor Vergata" University, Rome, Italy.
André ReisInstitute of Human Genetics, University of Erlangen-Nuremberg, Erlangen, Germany.
Anne BartonArthritis Research UK Centre for Genetics and Genomics, The University of Manchester, Manchester, UK.
Giuseppe NovelliDepartment of Biomedicine and Prevention, "Tor Vergata" University, Rome, Italy.
Augusto OrlandiAnatomic Pathology, Department of Biomedicine and Prevention, Tor Vergata University of Rome, Italy, Tor Vergata University Hospital, Rome, Italy.
Emiliano GiardinaMolecular Genetics Laboratory UILDM, Santa Lucia Foundation, Rome, Italy.
University of Rome Tor Vergata · ITFondazione Santa Lucia · ITFriedrich-Alexander-Universität Erlangen-Nürnberg · DECatholic University Our Lady of Good Counsel · ALInstitute of Applied Science and Intelligent Systems · ITUniversity of Manchester · GBVersus Arthritis · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, the genes associated with Psoriatic Arthritis (PsA) are principally involved in inflammation, immune response and epidermal differentiation, without any information about the relationship between disease and bone metabolism genes. Our work was focused on 5q31 locus, which contains several genetic variants significantly associated with PsA. The study involved 1526 subjects (500 PsA, 426 PsV, 600 controls). The region was evaluated by selecting and genotyping the SNPs of interest by Real Time PCR and direct sequencing. The results were subjected to biostatistic and bioinformatic analysis. The case-control study highlighted a significant association between

Indexed as

5q31 locusbone metabolismlinkage disequilibriumpsoriatic arthritissusceptibility

Identifiers

PMID29221136
PMCPMC5707030
OpenAlexW2751070662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.