Evidence map›Paper›PMID 29220696›Full record

ArticleRedox biology2018

Cardioprotection of CAPE-oNO

Dejuan Li, Xiaoling Wang, Qin Huang, Sai Li, You Zhou, Zhubo Li

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 2 syntheses or guidelines pooled it, 150 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Investigation of the protective effects of hydroxytyrosol on erythrocyte deformability during hind limb ischemia-reperfusion injury in rats.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
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  12. International journal of molecular sciences · 2025
    Article
  13. Review
  14. Volatile Oil FromJournal of inflammation research · 2025
    Article
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  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dejuan LiCollege of Pharmaceutical Sciences, Southwest University, No. 2, Tiansheng Road Beibei, Chongqing 400716, PR China.
Xiaoling WangCollege of Pharmaceutical Sciences, Southwest University, No. 2, Tiansheng Road Beibei, Chongqing 400716, PR China.
Qin HuangCollege of Pharmaceutical Sciences, Southwest University, No. 2, Tiansheng Road Beibei, Chongqing 400716, PR China.
Sai LiCollege of Pharmaceutical Sciences, Southwest University, No. 2, Tiansheng Road Beibei, Chongqing 400716, PR China.
You ZhouCollege of Biotechnology, Southwest University, Chongqing 400716, PR China.
Zhubo LiCollege of Pharmaceutical Sciences, Southwest University, No. 2, Tiansheng Road Beibei, Chongqing 400716, PR China. Electronic address: lizhubo2004@163.com.
Southwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caffeic acid phenethyl ester (CAPE) could ameliorate myocardial ischemia/reperfusion injury (MIRI) by various mechanisms, but there hadn't been any reports on that CAPE could regulate silent information regulator 1 (SIRT1) and endothelial nitric oxide synthase (eNOS) to exert cardioprotective effect. The present study aimed to investigate the cardioprotective potential of caffeic acid o-nitro phenethyl ester (CAPE-oNO

Indexed as

AnimalsApoptosisCaffeic AcidsCardiotonic AgentsCoronary VesselsGene Expression RegulationHumansMyocardial IschemiaMyocardial Reperfusion InjuryNF-kappa BNG-Nitroarginine Methyl EsterNiacinamideNitric Oxide Synthase Type IIIOxidative StressPhenylethyl AlcoholRatscaffeic acid phenethyl esterCaffeic AcidsCardiotonic AgentsNF-kappa BNG-Nitroarginine Methyl EsterNiacinamideNitric Oxide Synthase Type IIINos3 protein, ratPhenylethyl AlcoholSirt1 protein, ratSirtuin 1Caffeic acid o-nitro phenethyl ester (CAPE-oNO(2))Myocardial ischemia/reperfusion injury (MIRI)Reactive oxygen species (ROS)SIRT1/eNOS/NF-κB pathway

Identifiers

PMID29220696
PMCPMC5725281
OpenAlexW2769932289

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.