Evidence map›Paper›PMID 29220556›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2018

Drug treatment of hypertension in Sweden in relation to sex, age, and comorbidity.

Fredrik Wallentin, Björn Wettermark, Thomas Kahan

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  14. Cohort Profile: The Stockholm Diabetes Prevention Programme (SDPP).International journal of epidemiology · 2022
    Article
  15. Sex differences in arterial hypertension.European heart journal · 2022
    Review
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Fredrik WallentinKarolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Division of Cardiovascular Medicine, Stockholm, Sweden.
Björn WettermarkKarolinska Institutet, Department of Medicine/Solna, Centre for Pharmacoepidemiology, Stockholm, Sweden.
Thomas KahanKarolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Division of Cardiovascular Medicine, Stockholm, Sweden.ORCID 0000-0001-9909-4956

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors investigated antihypertensive drug treatment in Sweden using the Stockholm Regional Healthcare Data Warehouse, providing information on all healthcare consultations, diagnoses, hospitalizations, dispensed prescription drugs, sex, and age in 2.1 million persons. This cross-sectional analysis identified 292 428 individuals 20 years or older with hypertension (mean age 68 ± 13 years, 53% women). About half had no diabetes mellitus or cardiovascular comorbidity. The number of dispensed drugs was lower in women than in men (1.9 ± 1.3 vs 2.1 ± 1.5, P < .001). Women more often used diuretics, angiotensin receptor blockers, and β-blockers, while men used more angiotensin-converting enzyme inhibitors and calcium channel blockers (all P < .01). In women, 66% with diabetes mellitus and 72% with heart failure used angiotensin-converting enzyme inhibitors/angiotensin receptor blockers vs 76% and 79% in men (all P < .001, adjusted for age and comorbidity). Thus, sex differences in treatment prevail. There is room for improvement, which could reduce cardiovascular complications.

Indexed as

Antihypertensive AgentsHypertensionMedication Therapy ManagementAgedAged, 80 and overAge FactorsComorbidityCross-Sectional StudiesDiabetes MellitusFemaleHeart FailureHumansMaleMiddle AgedPrimary Health CareSex FactorsAntihypertensive Agentsantihypertensive agentsblood pressurecardiovascular diseasediabetes mellitushypertensionprimary health caresextreatment

Identifiers

PMID29220556
PMCPMC8031007

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.