ArticlePLoS medicine2017
Research on HIV cure: Mapping the ethics landscape.
Abstract read
In one paragraph
Article in PLoS medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- The HIV Reservoir and Immune Landscape Across the Life Course of Women: Implications for Cure Strategies.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Review
- Envisioning a Multidisciplinary HBV Cure Research Agenda.Current HIV/AIDS reports · 2025Review
- Integrating socio-behavioral, ethics, community, and translational science considerations in HIV cure research.Current opinion in HIV and AIDS · 2025Review
- Model-based evaluation of the impact of a potential HIV cure on HIV transmission dynamics.Nature communications · 2025Article
- Impact of an analytical treatment interruption on partners and family members of trial participants in Durban, South Africa: a qualitative study.Frontiers in public health · 2025Article
- 'With this study, we have hope that something is coming': community members' perceptions of HIV cure-related research in Durban, South Africa - a qualitative focus group study.HIV research & clinical practice · 2023Article
- Community engagement group model in basic and biomedical research: lessons learned from the BEAT-HIV Delaney Collaboratory towards an HIV-1 cure.Research involvement and engagement · 2023Article
- Ethical and practical considerations for cell and gene therapy toward an HIV cure: findings from a qualitative in-depth interview study in the United States.BMC medical ethics · 2022Article
- The perceived impact of an HIV cure by people living with HIV and key populations vulnerable to HIV in the Netherlands: A qualitative study.Journal of virus eradication · 2022Article
- Considerations for designing and implementing combination HIV cure trials: findings from a qualitative in-depth interview study in the United States.AIDS research and therapy · 2021Article
- Ethics of HIV cure research: an unfinished agenda.BMC medical ethics · 2021Review
- The LAIs Are Coming! Implementation Science Considerations for Long-Acting Injectable Antiretroviral Therapy in the United States: A Scoping Review.AIDS research and human retroviruses · 2021Article
- Reasons People Living with HIV Might Prefer Oral Daily Antiretroviral Therapy, Long-Acting Formulations, or Future HIV Remission Options.AIDS research and human retroviruses · 2020Article
- Altruism: Scoping review of the literature and future directions for HIV cure-related research.Journal of virus eradication · 2020Article
- Perceptions of HIV Virologic Control Strategies Among Younger and Older Age Groups of People Living with HIV in the United States: A Cross-Sectional Survey.AIDS research and human retroviruses · 2020Article
- The Dose Response: Perceptions of People Living with HIV in the United States on Alternatives to Oral Daily Antiretroviral Therapy.AIDS research and human retroviruses · 2020Article
- "I would really want to know that they had my back": Transgender women's perceptions of HIV cure-related research in the United States.PloS one · 2020Observational
- Applying the Behavioural and Social Sciences Research (BSSR) Functional Framework to HIV Cure Research.Journal of the International AIDS Society · 2019Review
- Fostering a prevention mindset for responsible gene editing.Accountability in research · 2019Article
- The psychology of "cure" - unique challenges to consent processes in HIV cure research in South Africa.BMC medical ethics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Karine DubéUniversity of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America.ORCID http://orcid.org/0000-0003-3458-1539
Laurie SylladefeatHIV Community Advisory Board (CAB), Seattle, Washington, United States of America.ORCID http://orcid.org/0000-0002-3746-7267
Lynda DeeamfAR Institute for HIV Cure Research CAB, San Francisco, California, United States of America.
Jeff TayloramfAR Institute for HIV Cure Research CAB, San Francisco, California, United States of America.
David EvansDelaney AIDS Research Enterprise (DARE) CAB, San Francisco, California, United States of America.ORCID http://orcid.org/0000-0001-5217-0368
Carl Dean BrutonCollaboratory of AIDS Researchers for Eradication (CARE) CAB, Palm Springs, California, and Chapel Hill, North Carolina, United States of America.
Adam GilberstonDepartment of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.ORCID http://orcid.org/0000-0002-4396-3638
Lisa GralinskiUniversity of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America.
Brandon BrownUniversity of California Riverside, Riverside, California, United States of America.
Asheley SkinnerUniversity of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America.
Bryan J WeinerUniversity of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America.
Sandra B GreeneUniversity of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina, United States of America.
Amy CorneliDuke Clinical Research Institute (DCRI), Durham, North Carolina, United States.
Adaora A AdimoraUNC Institute of Global Health and Infectious Diseases (IGHID), Chapel Hill, North Carolina, United States of America.
Joseph D TuckerUNC Institute of Global Health and Infectious Diseases (IGHID), Chapel Hill, North Carolina, United States of America.ORCID http://orcid.org/0000-0003-2804-1181
Stuart RennieDepartment of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Funding
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9MUsing NK Cells to eliminate the latent HIV reservoirU19AI096113 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LUCIW, PAUL · 2011 to 2015
$39.5MViral reservoirs and sanctuaries in HAART - treated patients: role and mechanismsU19AI096109 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SCHACKER, TIMOTHY W · 2011 to 2015
$29.5MDelaney AIDS Research Enterprise to Cure HIVUM1AI126611 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DEEKS, STEVEN GRANT, PICKER, LOUIS J. · 2016 to 2020
$27.9MCell and Gene Therapy for HIV CureUM1AI126623 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI JEROME, KEITH R, KIEM, HANS-PETER · 2016 to 2020
$24.2MCollaboratory of AIDS Researchers for Eradication (CARE)UM1AI126619 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MARGOLIS, DAVID M. · 2016 to 2020
$23.2MZFN-Modified Stem Cells for HIV EradicationU19AI096111 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI JEROME, KEITH R · 2011 to 2015
$20.8MHIV cure studies: risk, risk perception, and ethicsR01AI114617 · NIAID · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI EYAL, NIR · 2015 to 2018
$3.2MUnintended and Intended Implications of HIV Cure: A Social and Ethical AnalysisR01AI108366 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RENNIE, STUART, TUCKER, JOSEPH DAVID · 2013 to 2017
$2.9MNIAID NIH HHS P30 AI050410NIAID NIH HHS R01 AI108366NIAID NIH HHS R01 AI114617NIAID NIH HHS U19 AI096109NIAID NIH HHS U19 AI096111NIAID NIH HHS U19 AI096113NIAID NIH HHS UM1 AI126611NIAID NIH HHS UM1 AI126619NIAID NIH HHS UM1 AI126623
Abstract
In an essay, Karine Dubé and coauthors discuss the ethics of preclinical and clinical studies relevant to achieving an HIV cure.
Indexed as
AnimalsCost-Benefit AnalysisDiffusion of InnovationDisease Models, AnimalForecastingHealth Care CostsHealth Services AccessibilityHIV InfectionsHumansSpecies SpecificityTranslational Research, BiomedicalTreatment Outcome
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.