ArticlePLoS genetics2017
The pea branching RMS2 gene encodes the PsAFB4/5 auxin receptor and is involved in an auxin-strigolactone regulation loop.
Article in PLoS genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 51 citations in OpenAlex.
- Mutation of SCARECROW-LIKE28 or CYTOKININ OXIDASE3/5 suppresses rosette branching in Arabidopsis.Journal of experimental botany · 2026Article
- Enhanced Polar Auxin Transport and Reduced Brassinosteroid Activity Drive Internode Elongation in Chinese Fir (Plants (Basel, Switzerland) · 2026Article
- Creation of new rice germplasm with cross-resistance to auxin herbicides picloram and dicamba by genome editing of OsAFB4.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- The Role of FveAFB5 in Auxin-Mediated Responses and Growth in Strawberries.Plants (Basel, Switzerland) · 2024Article
- Innovations in functional genomics and molecular breeding of pea: exploring advances and opportunities.aBIOTECH · 2024Review
- Identification of potential auxin response candidate genes for soybean rapid canopy coverage through comparative evolution and expression analysis.Frontiers in plant science · 2024Article
- Strigolactones and Shoot Branching: What Is the Real Hormone and How Does It Work?Plant & cell physiology · 2023Review
- Lessons from a century of apical dominance research.Journal of experimental botany · 2023Article
- Identification of new potential downstream transcriptional targets of the strigolactone pathway including glucosinolate biosynthesis.Plant direct · 2023Article
- Jasmonic acid negatively regulates branch growth in pear.Frontiers in plant science · 2023Article
- Early defoliation induces auxin redistribution, promoting paradormancy release in pear buds.Plant physiology · 2022Article
- The Effects of High COInternational journal of molecular sciences · 2022Article
- The strigolactone receptor SlDWARF14 plays a role in photosynthetic pigment accumulation and photosynthesis in tomato.Plant cell reports · 2022Article
- Auxins in the right space and time regulate pea fruit development.Journal of experimental botany · 2022Article
- The molecular and genetic regulation of shoot branching.Plant physiology · 2021Review
- Auxin Interactions with Other Hormones in Plant Development.Cold Spring Harbor perspectives in biology · 2021Review
- Article
- Plant Inflorescence Architecture: The Formation, Activity, and Fate of Axillary Meristems.Cold Spring Harbor perspectives in biology · 2020Review
- Characterization and T-DNA insertion sites identification of a multiple-branches mutant br in Betula platyphylla × Betula pendula.BMC plant biology · 2019Article
- TIR1 auxin receptors are implicated in the differential response to 4-Cl-IAA and IAA in developing pea fruit.Journal of experimental botany · 2019Article
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Authors and funding
14 authors at 5 institutions in 3 countries.
Funding
Abstract
Strigolactones (SLs) are well known for their role in repressing shoot branching. In pea, increased transcript levels of SL biosynthesis genes are observed in stems of highly branched SL deficient (ramosus1 (rms1) and rms5) and SL response (rms3 and rms4) mutants indicative of negative feedback control. In contrast, the highly branched rms2 mutant has reduced transcript levels of SL biosynthesis genes. Grafting studies and hormone quantification led to a model where RMS2 mediates a shoot-to-root feedback signal that regulates both SL biosynthesis gene transcript levels and xylem sap levels of cytokinin exported from roots. Here we cloned RMS2 using synteny with Medicago truncatula and demonstrated that it encodes a putative auxin receptor of the AFB4/5 clade. Phenotypes similar to rms2 were found in Arabidopsis afb4/5 mutants, including increased shoot branching, low expression of SL biosynthesis genes and high auxin levels in stems. Moreover, afb4/5 and rms2 display a specific resistance to the herbicide picloram. Yeast-two-hybrid experiments supported the hypothesis that the RMS2 protein functions as an auxin receptor. SL root feeding using hydroponics repressed auxin levels in stems and down-regulated transcript levels of auxin biosynthesis genes within one hour. This auxin down-regulation was also observed in plants treated with the polar auxin transport inhibitor NPA. Together these data suggest a homeostatic feedback loop in which auxin up-regulates SL synthesis in an RMS2-dependent manner and SL down-regulates auxin synthesis in an RMS3 and RMS4-dependent manner.
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