Evidence map›Paper›PMID 29220078›Full record

ArticleCurrent protocols in bioinformatics2017

Using the Seven Bridges Cancer Genomics Cloud to Access and Analyze Petabytes of Cancer Data.

Raunaq Malhotra, Isheeta Seth, Erik Lehnert, Jing Zhao, Gaurav Kaushik, Elizabeth H Williams, Anurag Sethi, Brandi N Davis-Dusenbery

Abstract read
In one paragraph

Article in Current protocols in bioinformatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Raunaq MalhotraSeven Bridges Genomics Inc, Cambridge, Massachusetts.
Isheeta SethSeven Bridges Genomics Inc, Cambridge, Massachusetts.
Erik LehnertSeven Bridges Genomics Inc, Cambridge, Massachusetts.
Jing ZhaoSeven Bridges Genomics Inc, Cambridge, Massachusetts.
Gaurav KaushikSeven Bridges Genomics Inc, Cambridge, Massachusetts.
Elizabeth H WilliamsSeven Bridges Genomics Inc, Cambridge, Massachusetts.
Anurag SethiSeven Bridges Genomics Inc, Cambridge, Massachusetts.
Brandi N Davis-DusenberySeven Bridges Genomics Inc, Cambridge, Massachusetts.

Funding

NCI NIH HHS HHSN261201400008C
6 · The paper itself

Abstract

Next-generation sequencing has produced petabytes of data, but accessing and analyzing these data remain challenging. Traditionally, researchers investigating public datasets like The Cancer Genome Atlas (TCGA) would download the data to a high-performance cluster, which could take several weeks even with a highly optimized network connection. The National Cancer Institute (NCI) initiated the Cancer Genomics Cloud Pilots program to provide researchers with the resources to process data with cloud computational resources. We present protocols using one of these Cloud Pilots, the Seven Bridges Cancer Genomics Cloud (CGC), to find and query public datasets, bring your own data to the CGC, analyze data using standard or custom workflows, and benchmark tools for accuracy with interactive analysis features. These protocols demonstrate that the CGC is a data-analysis ecosystem that fully empowers researchers with a variety of areas of expertise and interests to collaborate in the analysis of petabytes of data. © 2017 by John Wiley & Sons, Inc.

Indexed as

Cloud ComputingComputational BiologyDatabases, GeneticData Interpretation, StatisticalGenomicsHigh-Throughput Nucleotide SequencingHumansMetadataNeoplasmsPilot Projectsbig datacancer genomicscloud computingcommon workflow languagereproduciblescalable

Identifiers

PMID29220078
PMCPMC5726550

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.