Evidence map›Paper›PMID 29218822›Full record

ReviewEuropean journal of neurology2018

European Academy of Neurology and European Stroke Organization consensus statement and practical guidance for pre-hospital management of stroke.

A Kobayashi, A Czlonkowska, G A Ford, A C Fonseca, G J Luijckx, J Korv, N Pérez de la Ossa, C Price, D Russell, A Tsiskaridze and 2 more

Erratum issued Registry-linked trialOpen access · bronzeAbstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in European journal of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06672757 (Use of App for Stroke Assessment VS Standard Level of Care During Prehospital Stroke Assessment), which is not on this map. Cited by 59 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 4 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06672757 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Use of App for Stroke Assessment VS Standard Level of Care During Prehospital Stroke Assessment

TypeinterventionalSponsorNaestved HospitalRan2024 to 2026Enrolled1,200ConditionsStroke, AcuteArmsCV_AID
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 4 syntheses or guidelines pooled it, 130 citations in OpenAlex.

  1. A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organization.International journal of stroke : official journal of the International Stroke Society · 2023
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. EDEN - Enhanced Dispatch for Efficient Neurointervention: mathematical model from national data.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Prehospital stroke detection scales: A head-to-head comparison of 7 scales in patients with suspected stroke.International journal of stroke : official journal of the International Stroke Society · 2025
    Review
  13. [Recent clinical studies and the S3 guidelines on stroke].Radiologie (Heidelberg, Germany) · 2025
    Review
  14. Observational
  15. Utility of AActa neurologica Belgica · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 10 countries.

A KobayashiInstitute of Psychiatry and Neurology, Interventional Stroke and Cerebrovascular Diseases Treatment Centre, Warsaw, Poland.ORCID 0000-0002-0312-6173
A CzlonkowskaSecond Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland.
G A FordDivision of Medical Sciences, Oxford University, Oxford, UK.
A C FonsecaDepartment of Neurology, Hospital de Santa Maria, University of Lisbon, Lisbon, Portugal.ORCID 0000-0001-6913-5526
G J LuijckxDepartment of Neurology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
J KorvDepartment of Neurology, Estonia Department of Neurology and Neurosurgery, Neurology Clinic, Tartu University Hospital, University of Tartu, Tartu, Estonia.
N Pérez de la OssaDepartment of Neurosciences, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, Spain.
C PriceInstitute of Neuroscience (Stroke Research Group), Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0003-3566-3157
D RussellDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
A TsiskaridzeDepartment of Neurology, Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia.
M Messmer-WullenAustrian Stroke Selfhelp Association, Lochau, Austria.
J De KeyserDepartment of Neurology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
University Medical Center Groningen · NLEuropean Federation of Pharmaceutical Industries and Associations · BEInstitute of Psychiatry and Neurology · PLMedical University of Warsaw · PLOslo University Hospital · NOTartu University Hospital · EETbilisi State University · GEThe Neurosciences Foundation · GBUniversitat Autònoma de Barcelona · ESUniversity of Lisbon · PTUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe reduction of delay between onset and hospital arrival and adequate pre-hospital care of persons with acute stroke are important for improving the chances of a favourable outcome. The objective is to recommend evidence-based practices for the management of patients with suspected stroke in the pre-hospital setting.

methodsThe GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology was used to define the key clinical questions. An expert panel then reviewed the literature, established the quality of the evidence, and made recommendations.

resultsDespite very low quality of evidence educational campaigns to increase the awareness of immediately calling emergency medical services are strongly recommended. Moderate quality evidence was found to support strong recommendations for the training of emergency medical personnel in recognizing the symptoms of a stroke and in implementation of a pre-hospital 'code stroke' including highest priority dispatch, pre-hospital notification and rapid transfer to the closest 'stroke-ready' centre. Insufficient evidence was found to recommend a pre-hospital stroke scale to predict large vessel occlusion. Despite the very low quality of evidence, restoring normoxia in patients with hypoxia is recommended, and blood pressure lowering drugs and treating hyperglycaemia with insulin should be avoided. There is insufficient evidence to recommend the routine use of mobile stroke units delivering intravenous thrombolysis at the scene. Because only feasibility studies have been reported, no recommendations can be provided for pre-hospital telemedicine during ambulance transport.

conclusionsThese guidelines inform on the contemporary approach to patients with suspected stroke in the pre-hospital setting. Further studies, preferably randomized controlled trials, are required to examine the impact of particular interventions on quality parameters and outcome.

Indexed as

ConsensusEmergency Medical ServicesEmergency Medical TechniciansHumansNeurologyStrokeambulancepre-hospital carestroke

Identifiers

PMID29218822
OpenAlexW2774600063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.