ArticlePediatric blood & cancer2018
Illness and end-of-life experiences of children with cancer who receive palliative care.
Article in Pediatric blood & cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- The Impact of Specialty Palliative Care in Pediatric Oncology: A Systematic Review.Journal of pain and symptom management · 2021Pooled it
- Decision-Making at End-of-Life for Children With Cancer: A Systematic Review and Meta-Bioethical Analysis.Frontiers in oncology · 2021Pooled it
- Specialist paediatric palliative care for children and young people with cancer: A mixed-methods systematic review.Palliative medicine · 2020Pooled it
- Impact of a shared pediatric palliative care program on end-of-life care trends among children: a 10-year retrospective study in Taiwan.BMC palliative care · 2026Article
- Describing Deaths over a Decade: The Final Week of Life Among Hospitalized Children with Cancer.Children (Basel, Switzerland) · 2026Article
- Relationship Between Social Determinants of Health and Domains of Care Addressed During Pediatric Palliative Care Visits for Children with Cancer.Children (Basel, Switzerland) · 2025Article
- Needs, status and future directions in palliative care for children with cancer: an insight into the Italian situation.Frontiers in oncology · 2025Review
- Electronic Patient Reported Outcomes Measures (e-PROMs) in Pediatric Palliative Oncology Care: A Scoping Review.Journal of palliative care · 2024Article
- Harnessing Natural Language Processing to Assess Quality of End-of-Life Care for Children With Cancer.JCO clinical cancer informatics · 2024Article
- Access to legacy-oriented interventions at end of life for pediatric oncology patients: A decedent cohort review.Pediatric blood & cancer · 2024Article
- Application of Instrumental Variable Analysis in Pediatric End-of-Life Research: A Case Study.Western journal of nursing research · 2023Article
- Regional blocks for pain control at the end of life in pediatric oncology.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Virtual reality for pain and anxiety of pediatric oncology patients: A systematic review and meta-analysis.Asia-Pacific journal of oncology nursing · 2022Review
- End-of-life care quality for children with cancer who receive palliative care.Pediatric blood & cancer · 2022Article
- Voicing their choices: Advance care planning with adolescents and young adults with cancer and other serious conditions.Palliative & supportive care · 2022Article
- The do-not-resuscitate-like (DNRL) order, a medical directive for limiting life-sustaining treatment in the end-of-life care of children with cancer: experience of major cancer center in Brazil.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Observational
- Palliative Care in Pediatric Oncology and Hematopoietic Stem Cell Transplantation.Current oncology reports · 2022Review
- Article
- Compassionate de-escalation of life-sustaining treatments in pediatric oncology: An opportunity for palliative care and intensive care collaboration.Frontiers in oncology · 2022Article
- Differences in characteristics of children with cancer who receive standard versus concurrent hospice care.Pediatric blood & cancer · 2021Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThe field of pediatric palliative oncology is newly emerging. Little is known about the characteristics and illness experiences of children with cancer who receive palliative care (PC).
methodsA retrospective cohort study of 321 pediatric oncology patients enrolled in PC who died between 2011 and 2015 was conducted at a large academic pediatric cancer center using a comprehensive standardized data extraction tool.
resultsThe majority of pediatric palliative oncology patients received experimental therapy (79.4%), with 40.5% enrolled on a phase I trial. Approximately one-third received cancer-directed therapy during the last month of life (35.5%). More than half had at least one intensive care unit hospitalization (51.4%), with this subset demonstrating considerable exposure to mechanical ventilation (44.8%), invasive procedures (20%), and cardiopulmonary resuscitation (12.1%). Of the 122 patients who died in the hospital, 44.3% died in the intensive care unit. Patients with late PC involvement occurring less than 30 days before death had higher odds of dying in the intensive care unit over the home/hospice setting compared to those with earlier PC involvement (OR: 4.7, 95% CI: 2.47-8.97, P < 0.0001).
conclusionsChildren with cancer who receive PC experience a high burden of intensive treatments and often die in inpatient intensive care settings. Delayed PC involvement is associated with increased odds of dying in the intensive care unit. Prospective investigation of early PC involvement in children with high-risk cancer is needed to better understand potential impacts on cost-effectiveness, quality of life, and delivery of goal concordant care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.