Evidence map›Paper›PMID 29218676›Full record

Observational studySurgical endoscopy2018

Morbidity and mortality from a propensity score-matched, prospective cohort study of laparoscopic versus open total gastrectomy for gastric cancer: data from a nationwide web-based database.

Tsuyoshi Etoh, Michitaka Honda, Hiraku Kumamaru, Hiroaki Miyata, Kazuhiro Yoshida, Yasuhiro Kodera, Yoshihiro Kakeji, Masafumi Inomata, Hiroyuki Konno, Yasuyuki Seto and 2 more

2 registry-linked trialsAbstract readComparative StudyMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03500471 completednot on this map

Safety and Feasibility Between Robotic and Laparoscopic Total Gastrectomy With D2 Lymphadenectomy for Locally Advanced Gastric Cancer：A Prospective Cohort Study

TypeobservationalSponsorSouthwest Hospital, ChinaRan2018 to 2021Enrolled142ConditionsGastric CancerArmsRobotic-assisted Total Gastrectomy, Laparoscopic-assisted Total Gastrectomy
NCT05181306 completednot on this map

Long-term Oncologic Outcomes of Robotic Versus Laparoscopic Total Gastrectomy for Advanced Gastric Cancer: A Propensity Score Matching Study

TypeobservationalSponsorSouthwest Hospital, ChinaRan2010 to 2016Enrolled430ConditionsGastric CancerArmsRobotic-assisted Total Gastrectomy with D2 Lymphadenectomy, Laparoscopic-assisted Total Gastrectomy with D2 Lymphadenectomy
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Single-arm confirmatory trial of laparoscopy-assisted total or proximal gastrectomy with nodal dissection for clinical stage I gastric cancer: Japan Clinical Oncology Group study JCOG1401.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019
    Trial
  4. Clinical advantages of robotic gastrectomy for gastric cancer over conventional laparoscopic approach: a retrospective cohort study using a nationwide registry database in Japan.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Escalation and de-escalation in surgery for gastric cancer.International journal of clinical oncology · 2025
    Review
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  11. Review
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Tsuyoshi EtohDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Hasama-machi, Oita, 879-5593, Japan. teto@oita-u.ac.jp.
Michitaka HondaDepartment of Minimal Invasive Surgical and Medical Oncology, Fukushima Medical University, Fukushima, Japan.
Hiraku KumamaruDepartment of Healthcare Quality Assessment, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Hiroaki MiyataDepartment of Health Policy and Management, School of Medicine, Keio University, Tokyo, Japan.
Kazuhiro YoshidaDepartment of Surgical Oncology, Graduate School of Medicine, Gifu University, Gifu, Japan.
Yasuhiro KoderaDepartment of Gastroenterological Surgery, Nagoya University, Graduate School of Medicine, Nagoya, Japan.
Yoshihiro KakejiDivision of Gastrointestinal Surgery, Department of Surgery, Graduate School of Medicine, Kobe University, Kobe, Japan.
Masafumi InomataDepartment of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine, Hasama-machi, Oita, 879-5593, Japan.
Hiroyuki KonnoDatabase Committee, The Japanese Society of Gastroenterological Surgery, Tokyo, Japan.
Yasuyuki SetoThe Japanese Society of Gastroenterological Surgery, Tokyo, Japan.
Seigo KitanoOita University, Oita, Japan.
Naoki HikiDepartment of Gastroenterological Surgery, Gastroenterological Center, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
Oita University · JPThe Japanese Society of Gastroenterological Surgery · JPFukushima Medical University · JPGifu University · JPJapanese Foundation For Cancer Research · JPKeio University · JPKobe University · JPNagoya University · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundControversy persists regarding the technical feasibility of laparoscopic total gastrectomy (LTG), and to our knowledge, no prospective study with a sample size sufficient to investigate its safety has been reported. We aimed to compare the postoperative morbidity and mortality rates in patients undergoing LTG and open total gastrectomy (OTG) for gastric cancer in prospectively enrolled cohort using nationwide web-based registry.

methodsFrom August 2014 to July 2015, consecutive patients undergoing LTG or OTG (925 and 1569 patients, respectively) at the participating institutions were enrolled prospectively into the National Clinical Database registration system. We constructed propensity score (PS) models separately in four facility yearly case-volume groups, and evaluated the postoperative morbidity and mortality in PS-matched 1024 patients undergoing LTG or OTG.

resultsThe incidence of overall morbidity were 84 (16.4%) in the OTG and 54 (10.3%) in the LTG groups (p = 0.01).The incidence of anastomotic leakage and pancreatic fistula grade B or above were not significantly different between the two groups (LTG 5.3% vs. OTG 6.1%, p = 0.59, LTG 2.7% vs. OTG 3.7%, p = 0.38, respectively). There were also no significant differences in the 30-day and in-hospital mortality rates between the two groups (LTG 0.2% vs. OTG 0.4%, p = 0.56; LTG 0.4% vs. OTG 0.4%, p = 1.00, respectively).

conclusionThe results from our nationally representative data analysis showed that LTG could be a safe procedure to treat gastric cancer compared to OTG. The indication for LTG should be considered carefully in a clinical setting.

Indexed as

Propensity ScoreRegistriesAgedFemaleFollow-Up StudiesGastrectomyHospital MortalityHumansIncidenceJapanLaparoscopyMalePostoperative ComplicationsPrognosisProspective StudiesStomach NeoplasmsLaparoscopic total gastrectomyNational Clinical Database registration systemProspective cohort study

Identifiers

PMID29218676
OpenAlexW2771190643

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.