Evidence map›Paper›PMID 29218639›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2018

Histidine tracts in human transcription factors: insight into metal ion coordination ability.

Aleksandra Hecel, Joanna Wątły, Magdalena Rowińska-Żyrek, Jolanta Świątek-Kozłowska, Henryk Kozłowski

Open access · hybridAbstract read
In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Aleksandra HecelFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383, Wrocław, Poland. aleksandra.hecel@chem.uni.wroc.pl.
Joanna WątłyFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383, Wrocław, Poland.
Magdalena Rowińska-ŻyrekFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383, Wrocław, Poland.
Jolanta Świątek-KozłowskaPublic Higher Medical Professional School in Opole, Katowicka 68, 45-060, Opole, Poland.
Henryk KozłowskiPublic Higher Medical Professional School in Opole, Katowicka 68, 45-060, Opole, Poland. henryk.kozlowski@chem.uni.wroc.pl.
University of Wrocław · PLPublic Higher Medical Professional School in Opole · PLWroclaw Research Centre EIT+ (Poland) · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consecutive histidine repeats are chosen both by nature and by molecular biologists due to their high affinity towards metal ions. Screening of the human genome showed that transcription factors are extremely rich in His tracts. In this work, we examine two of such His-rich regions from forkhead box and MAFA proteins-MB3 (contains 18 His) and MB6 (with 21 His residues), focusing on the affinity and binding modes of Cu

Indexed as

Amino Acid SequenceCoordination ComplexesCopperForkhead Transcription FactorsHistidineHumansHydrogen-Ion ConcentrationMaf Transcription Factors, LargeNerve Tissue ProteinsPeptide FragmentsProtein BindingZincCoordination ComplexesCopperForkhead Transcription FactorsFOXG1 protein, humanHistidineMAFA protein, humanMaf Transcription Factors, LargeNerve Tissue ProteinsPeptide FragmentsZincBinding affinityHomeostasisLigand bindingMass spectrometryPeptideThermodynamics

Identifiers

PMID29218639
PMCPMC5756558
OpenAlexW2772885235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.