ArticleDysphagia2018
Effect of Body Position on Pharyngeal Swallowing Pressures Using High-Resolution Manometry.
Article in Dysphagia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Impact of Head and Neck Posture on Swallowing Kinematics and Muscle Activation: A Systematic Review.Dysphagia · 2025Pooled it
- A systematic review of current methodology of high resolution pharyngeal manometry with and without impedance.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019Pooled it
- The effects of noninvasive respiratory support on swallowing physiology, airway protection, and respiratory-swallow pattern in adults: A systematic review.Respiratory medicinePooled it
- Effect of body inclination on suprahyoid muscle activity during repetitive voluntary swallowing: A randomized crossover study.Physiological reports · 2025Trial
- How a personalised transportable folding device for seating impacts dysphagia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Trial
- Pressure and Timing Differences Between Volitional and Non-Cued Saliva Swallows Measured with Pharyngeal High-Resolution Manometry.Dysphagia · 2026Article
- Evaluation of Dysphagia in Myositis and Muscular Dystrophy Using Real-Time MRI and Quantitative Muscle Ultrasound.Journal of cachexia, sarcopenia and muscle · 2026Article
- Article
- Preliminary Characterization of Proximal Versus Distal Esophageal Function in Healthy, Asymptomatic Adults.Neurogastroenterology and motility · 2026Article
- Evaluating Behavioural Interventions for Oropharyngeal Dysphagia in Adults: A Systematic Review and Meta-Analysis of Swallowing Manoeuvres, Exercises, and Postural Techniques.Journal of clinical medicine · 2025Review
- Normative High-Resolution Pharyngeal Manometry: Impact of Age, Size of System, and Sex on Primary Metrics and Pressure Stability.Dysphagia · 2024Article
- Practical recommendations for swallowing and speaking during NIV in people with neuromuscular disorders.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2024Review
- Deglutition and the Regulation of the Swallow Motor Pattern.Physiology (Bethesda, Md.) · 2023 · on this mapReview
- Pharyngeal Pressure Variability During Volitional Swallowing Maneuvers.Journal of speech, language, and hearing research : JSLHR · 2022Article
- Altered swallowing biomechanics in people with moderate-severe obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Effect of Bridge Position Swallow on Esophageal Motility in Healthy Individuals Using High-Resolution Manometry.Dysphagia · 2021Article
- Swallowing Pressure Variability as a Function of Pharyngeal Region, Bolus Volume, Age, and Sex.The Laryngoscope · 2021Article
- Pressure abnormalities in patients with Zenker's diverticulum using pharyngeal high-resolution manometry.Laryngoscope investigative otolaryngology · 2020Article
- Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The effect of body position and gravitational pull on the complex pressure-driven process of pharyngeal swallowing remains unknown. Using high-resolution manometry (HRM), this study aims to identify positional adaptations of pharyngeal physiology by evaluating swallowing pressure patterns in a series of inverted body positions. Ten healthy adults each underwent swallowing tasks with pharyngeal HRM at six body positions using an inversion table (0°[upright], 45°, 90°[supine], 110°, 135°, and 180°[fully inverted]). Repeated measures ANOVA was used to assess impact of position on pressure parameters, and pharyngeal-UES pressure gradients translate. Velopharyngeal pressures varied by position (P < 0.001), with significantly higher pressures generated with inversion ≥90°, compared with upright and 45°. Change in position did not significantly affect common mesopharyngeal pressures or swallowing pressure durations. UES valving mechanisms were preserved during inversion, with subtle variations observed in integral pressures (P = 0.011). Pharyngeal-UES pressure gradients changed with position (P < 0.01), increasing with inversion > 90° compared to upright and 45°. Mechanisms of deglutition may differ with position and relative direction of gravity, particularly when at > 45° inclination. Increased palatal pressure is generated in the upside-down position to achieve nasopharyngeal closure and prevent regurgitation. While other classically measured pressures may not consistently differ with positioning, many individuals exhibit adaptations in pressure gradients when inverted, likely due to a combination of changes in pharyngeal driving force and UES opening mechanisms. Identification of these changes, relative to position, further builds on our understanding of the adaptability of the pharyngeal swallowing system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.