Evidence map›Paper›PMID 29218460›Full record

ArticleJournal of medical systems2017

A Novel Adaptive Deformable Model for Automated Optic Disc and Cup Segmentation to Aid Glaucoma Diagnosis.

Muhammad Salman Haleem, Liangxiu Han, Jano van Hemert, Baihua Li, Alan Fleming, Louis R Pasquale, Brian J Song

Abstract read
In one paragraph

Article in Journal of medical systems, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Clinical validation ofIndian journal of ophthalmology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muhammad Salman HaleemSchool of Computing, Mathematics and Digital Technology, Manchester Metropolitan University, Manchester, M1 5GD, UK. m.haleem@mmu.ac.uk.ORCID http://orcid.org/0000-0001-5946-6567
Liangxiu HanSchool of Computing, Mathematics and Digital Technology, Manchester Metropolitan University, Manchester, M1 5GD, UK.
Jano van HemertOptos Plc, Queensferry House, Carnegie Business Campus, Enterprise Way, Dunfermline, Scotland, KY11 8GR, UK.
Baihua LiDepartment of Computer Science, Loughborough University, Loughborough, LE11 3TU, UK.
Alan FlemingOptos Plc, Queensferry House, Carnegie Business Campus, Enterprise Way, Dunfermline, Scotland, KY11 8GR, UK.
Louis R PasqualeDepartment of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.
Brian J SongDepartment of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.

Funding

Mass Eye and Ear-Vision Clinical Scientist Development ProgramK12EY016335 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Reza Dana · 2004 to 2026
$12.3M
Engineering and Physical Sciences Research Council EP/J50063X/1NEI NIH HHS K12 EY016335
6 · The paper itself

Abstract

This paper proposes a novel Adaptive Region-based Edge Smoothing Model (ARESM) for automatic boundary detection of optic disc and cup to aid automatic glaucoma diagnosis. The novelty of our approach consists of two aspects: 1) automatic detection of initial optimum object boundary based on a Region Classification Model (RCM) in a pixel-level multidimensional feature space; 2) an Adaptive Edge Smoothing Update model (AESU) of contour points (e.g. misclassified or irregular points) based on iterative force field calculations with contours obtained from the RCM by minimising energy function (an approach that does not require predefined geometric templates to guide auto-segmentation). Such an approach provides robustness in capturing a range of variations and shapes. We have conducted a comprehensive comparison between our approach and the state-of-the-art existing deformable models and validated it with publicly available datasets. The experimental evaluation shows that the proposed approach significantly outperforms existing methods. The generality of the proposed approach will enable segmentation and detection of other object boundaries and provide added value in the field of medical image processing and analysis.

Indexed as

Machine LearningAlgorithmsGlaucomaHumansImage Processing, Computer-AssistedOptic DiskPattern Recognition, AutomatedComputer-aided retinal disease diagnosisGlaucomaMachine learningMedical image processing and analysis

Identifiers

PMID29218460
PMCPMC5719827

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.