ReviewPflugers Archiv : European journal of physiology2018
The extraordinary AFD thermosensor of C. elegans.
Review in Pflugers Archiv : European journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- Starvation transforms signal encoding ineLife · 2026Article
- Starvation transforms signal encoding inbioRxiv : the preprint server for biology · 2026Article
- Experience-Dependent Gain Modulation Drives Thermosensory Responses in Behavior.bioRxiv : the preprint server for biology · 2026Article
- Article
- A Glial Hub-and-Spoke Circuitry in C. elegans orchestrates bidirectional thermosensation.Nature communications · 2026Article
- Roles of Cyclic Nucleotide Phosphodiesterases in Signal Transduction Pathways in the NematodeCells · 2025Review
- Article
- Configuration of electrical synapses filters sensory information to drive behavioral choices.Cell · 2025Article
- C. elegans PPEF-type phosphatase (Retinal degeneration C ortholog) functions in diverse classes of cilia to regulate nematode behaviors.Scientific reports · 2024Article
- An activity-regulated transcriptional program directly drives synaptogenesis.Nature neuroscience · 2024Article
- A tonically active master neuron modulates mutually exclusive motor states at two timescales.Science advances · 2024Article
- Feedforward and feedback mechanisms cooperatively regulate rapid experience-dependent response adaptation in a single thermosensory neuron type.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Neuron cilia restrain glial KCC-3 to a microdomain to regulate multisensory processing.Cell reports · 2024Article
- Introduction toJournal of nematology · 2024Article
- Glia in Invertebrate Models: Insights from Caenorhabditis elegans.Advances in neurobiology · 2024Review
- The AFD-expressed SRTX-1 GPCR does not contribute to AFD thermosensory functions.microPublication biology · 2024Article
- Feedforward and feedback mechanisms cooperatively regulate rapid experience-dependent response adaptation in a single thermosensory neuron type.bioRxiv : the preprint server for biology · 2023Article
- Hunting with heat: thermosensory-driven foraging in mosquitoes, snakes and beetles.The Journal of experimental biology · 2023Article
- Article
- Multisite regulation integrates multimodal context in sensory circuits to control persistent behavioral states in C. elegans.Nature communications · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The nematode C. elegans exhibits complex thermal experience-dependent navigation behaviors in response to environmental temperature changes of as little as 0.01°C over a > 10°C temperature range. The remarkable thermosensory abilities of this animal are mediated primarily via the single pair of AFD sensory neurons in its head. In this review, we describe the contributions of AFD to thermosensory behaviors and temperature-dependent regulation of organismal physiology. We also discuss the mechanisms that enable this neuron type to adapt to recent temperature experience and to exhibit extraordinary thermosensitivity over a wide dynamic range.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.