Evidence map›Paper›PMID 29218453›Full record

ArticlePflugers Archiv : European journal of physiology2018

Energy depletion and not ROS formation is a crucial step of glucolipotoxicity (GLTx) in pancreatic beta cells.

Morgana Barroso Oquendo, Nikolas Layer, Rebecca Wagner, Peter Krippeit-Drews, Gisela Drews

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Morgana Barroso OquendoInstitute of Pharmacy, Department of Pharmacology, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.
Nikolas LayerInstitute of Pharmacy, Department of Pharmacology, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.
Rebecca WagnerInstitute of Pharmacy, Department of Pharmacology, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.
Peter Krippeit-DrewsInstitute of Pharmacy, Department of Pharmacology, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.
Gisela DrewsInstitute of Pharmacy, Department of Pharmacology, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany. gisela.drews@uni-tuebingen.de.ORCID 0000-0002-0756-4816
University of Tübingen · DE

Funding

Deutsche Forschungsgemeinschaft DR225/11-1
6 · The paper itself

Abstract

We have shown previously that genetic or pharmacological deletion of K

Indexed as

ApoptosisEnergy MetabolismAdenosine TriphosphateAnimalsCells, CulturedGliclazideGlucoseHypoglycemic AgentsInsulinInsulin-Secreting CellsKATP ChannelsMembrane Potential, MitochondrialMiceMice, Inbred C57BLReactive Oxygen SpeciesTolbutamideAdenosine TriphosphateGliclazideGlucoseHypoglycemic AgentsInsulinKATP ChannelsReactive Oxygen SpeciesTolbutamideBeta cellExocytosisGliclazideGlucolipotoxicityReactive oxygen speciesStimulus-secretion coupling

Identifiers

PMID29218453
OpenAlexW2773351419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.