Evidence map›Paper›PMID 29218320›Full record

ArticleEndoscopy international open2017

Predictive relevance of lymphovascular invasion in T1 colorectal cancer before endoscopic treatment.

Kazuya Inoki, Taku Sakamoto, Hiroyuki Takamaru, Masau Sekiguchi, Masayoshi Yamada, Takeshi Nakajima, Takahisa Matsuda, Hirokazu Taniguchi, Shigeki Sekine, Yukihide Kanemitsu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Endoscopy international open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Kazuya InokiEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Taku SakamotoEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Hiroyuki TakamaruEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Masau SekiguchiEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Masayoshi YamadaEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Takeshi NakajimaEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Takahisa MatsudaEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Hirokazu TaniguchiPathology and Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan.
Shigeki SekinePathology and Clinical Laboratory Division, National Cancer Center Hospital, Tokyo, Japan.
Yukihide KanemitsuColorectal Surgery Division, National Cancer Center Hospital, Tokyo, Japan.
Yuichiro OheCourse of Advanced Clinical Research of Cancer, Juntendo University Graduate School of Medicine, National Cancer Center Hospital, Tokyo, Japan.
Yutaka SaitoEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
National Cancer Center Hospital East · JPTokyo National Hospital · JPJuntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimThe depth of tumor invasion is currently the only reliable predictive risk factor for lymph node metastasis before endoscopic treatment for colorectal cancer. However, the most important factor to predict lymph node metastasis has been suggested to be lymphovascular invasion rather than the depth of invasion. Thus, the aim of this study was to investigate the predictive relevance of lymphovascular invasion before endoscopic treatment.

methodsThe data on pT1 colorectal cancers that were resected endoscopically or surgically from 2007 to 2015 were retrospectively reviewed. The cases were categorized into two groups: positive or negative for lymphovascular invasion. The following factors were evaluated by univariate and multivariate analyses: age and sex of the patients; location, size, and morphology of the lesion; and depth of invasion.

resultsThe positive and negative groups included 229 and 457 cases, respectively. Younger age (

conclusionYounger age, presence of depression, T1b, and non-LST are associated with lymphovascular invasion. Therefore, careful pathological diagnosis and surveillance are necessary for lesions demonstrating any of these four factors.

Identifiers

PMID29218320
PMCPMC5718905
OpenAlexW2775199028

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.