Evidence map›Paper›PMID 29218082›Full record

ArticleAmerican journal of translational research2017

Functional characterization of CXCR4 in mediating the expression of protein C system in experimental ulcerative colitis.

Xuhong Lin, Huichao Wang, Yuxia Li, Jingnan Yang, Ruilin Yang, Dandan Wei, Junjie Zhang, Desheng Yang, Bin Wang, Xuequn Ren and 1 more

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Exploring the Therapeutic Potentials and Molecular Mechanisms ofPreventive nutrition and food science · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Role of Vitamin K in Intestinal Health.Frontiers in immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xuhong LinDepartment of Clinical Laboratory, Translational Medicine Center, Huaihe Hospital Affiliated to Henan UniversityKaifeng 475000, Henan, China.
Huichao WangDepartment of Nephrology, First Affiliated Hospital of Henan UniversityKaifeng 475000, Henan, China.
Yuxia LiDepartment of Clinical Laboratory, Translational Medicine Center, Huaihe Hospital Affiliated to Henan UniversityKaifeng 475000, Henan, China.
Jingnan YangDepartment of Clinical Laboratory, Translational Medicine Center, Huaihe Hospital Affiliated to Henan UniversityKaifeng 475000, Henan, China.
Ruilin YangDepartment of Clinical Laboratory, Translational Medicine Center, Huaihe Hospital Affiliated to Henan UniversityKaifeng 475000, Henan, China.
Dandan WeiDepartment of Clinical Laboratory, Translational Medicine Center, Huaihe Hospital Affiliated to Henan UniversityKaifeng 475000, Henan, China.
Junjie ZhangDepartment of General Surgery, Huaihe Hospital Affiliated to Henan UniversityKaifeng 475000, Henan, China.
Desheng YangDepartment of Gastroenterology, Huaihe Hospital Affiliated to Henan UniversityKaifeng 475000, Henan, China.
Bin WangDepartment of Clinical Laboratory, Translational Medicine Center, Huaihe Hospital Affiliated to Henan UniversityKaifeng 475000, Henan, China.
Xuequn RenDepartment of General Surgery, Huaihe Hospital Affiliated to Henan UniversityKaifeng 475000, Henan, China.
Guanchang ChengDepartment of Cardiovascular Medicine, Huaihe Hospital Affiliated to Henan UniversityKaifeng 475000, Henan, China.
Henan University Huaihe Hospital and Huaihe Clinical Institute · CNFirst Affiliated Hospital of Henan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to explore the role of CXCR4 and protein C system (PCS) in the experimental ulcerative colitis (UC). The expression of CXCR3, CCR10, and CXCR4 in dextran sulfate sodium (DSS)-induced colitis mouse model was measured by immunohistochemistry and western blot analysis.

Indexed as

CXCR4protein Culcerative colitis

Identifiers

PMID29218082
PMCPMC5714768
OpenAlexW3009467396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.