ArticleActa medica Lituanic2017
Investigation of markers of allergic sensitization and viral infections in children with allergy and asthma.
Article in Acta medica Lituanic, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Allergen-specific IgE and IgG4 patterns among patients with different allergic diseases.The World Allergy Organization journal · 2018Article
- Multifactorial analysis of willingness to undergo subcutaneous allergen immunotherapy in pediatric patients.Pakistan journal of medical sciencesArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
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Abstract
backgroundAllergic diseases are the most prevalent chronic diseases in the developed countries. It is believed that early allergic sensitization and respiratory viral infections play an important role in the development of allergic diseases and asthma.
methodsThe current study investigated the correlation between asthma, allergy, and various markers - allergen-specific IgE, IgG4 and IgA, ECP, IgM, and IgG antibodies against respiratory viruses hRSV and hPIV1-4 - in blood serum samples from 80 children (mean age 5.2 years) recruited from the Lithuanian birth cohort. Children were divided into three groups according to their diagnosis: asthma (
resultsBased on retrospective data, airway infections and bronchitis by the age of two years were associated with asthma in later childhood. The presence of IgM and IgG antibodies against hRSV and hPIV1-4 at the age of five years were not associated with asthma and allergy: a high rate of persistent or past respiratory viral infections was revealed in all three groups. Among allergic children, increased levels of allergen-specific IgE and d1-specific IgG4 were determined.
conclusionThe current study provides new insights into the relationships between allergic sensitization and respiratory virus infections in children.
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