Evidence map›Paper›PMID 29217827›Full record

ArticleScientific reports2017

Genome-Wide Association Study of Male Sexual Orientation.

Alan R Sanders, Gary W Beecham, Shengru Guo, Khytam Dawood, Gerulf Rieger, Judith A Badner, Elliot S Gershon, Ritesha S Krishnappa, Alana B Kolundzija, Jubao Duan and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
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  7. Can the proximal humeral ossification system (PHOS) effectively guide brace weaning in patients with adolescent idiopathic scoliosis?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
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  12. The De-Scent of Sexuality: Should We Smell a Rat?Archives of sexual behavior · 2021
    Article
  13. Effect of adverse childhood experiences and DNA methylation on male sexual orientation.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Article
  14. Article
  15. Sexual partner preference in animals and humans.Neuroscience and biobehavioral reviews · 2020
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 18 institutions in 3 countries.

Alan R SandersDepartment of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem Research Institute, Evanston, Illinois, 60201, United States of America. alan.sanders.md@gmail.com.
Gary W BeechamDepartment of Human Genetics, University of Miami, Miami, Florida, 33136, United States of America.
Shengru GuoDepartment of Human Genetics, University of Miami, Miami, Florida, 33136, United States of America.
Khytam DawoodDepartment of Psychology, Pennsylvania State University, University Park, Pennsylvania, 16802, United States of America.
Gerulf RiegerDepartment of Psychology, University of Essex, Colchester, England, CO4 3SQ, United Kingdom.
Judith A BadnerDepartment of Psychiatry, Rush University Medical Center, Chicago, Illinois, 60612, United States of America.
Elliot S GershonDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, 60637, United States of America.
Ritesha S KrishnappaDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Elmhurst, New York, 11373, United States of America.
Alana B KolundzijaDepartment of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, New York, 10027, United States of America.
Jubao DuanDepartment of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem Research Institute, Evanston, Illinois, 60201, United States of America.
MGS Collaboration
Pablo V GejmanDepartment of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem Research Institute, Evanston, Illinois, 60201, United States of America.
J Michael BaileyDepartment of Psychology, Northwestern University, Evanston, Illinois, 60208, United States of America.
Eden R MartinDepartment of Human Genetics, University of Miami, Miami, Florida, 33136, United States of America.
University of Miami · USIcahn School of Medicine at Mount Sinai · USNorthShore University HealthSystem · USUniversity of Chicago · USUniversity of Colorado Denver · USWashington University in St. Louis · USColumbia University · USDivision of Cancer Epidemiology and GeneticsEmory University · USLouisiana State University Health Sciences Center New Orleans · USNorthwestern University · USPark Centre for Mental Health · AUPennsylvania State University · USRush University Medical Center · USStanford University · USUniversity of California, San Francisco · USUniversity of Essex · GBUniversity of Iowa · US

Funding

MOLECULAR GENETICS OF SCHIZOPHRENIAR01MH059571 · NIMH · UNIVERSITY OF CHICAGO · PI GEJMAN, PABLO V. · 1999 to 2007
$8.0M
A Genome-Wide Association Study of SchizophreniaU01MH079469 · NIMH · NORTHSHORE UNIVERSITY HEALTHSYSTEM · PI GEJMAN, PABLO V. · 2007 to 2009
$4.4M
Molecular Genetic Study of Sexual OrientationR01HD041563 · NICHD · NORTHSHORE UNIV HEALTHSYSTEM RES INST · PI SANDERS, ALAN R · 2003 to 2007
$3.7M
MOLECULAR GENETICS OF SCHIZOPHRENIAR01MH060879 · NIMH · WASHINGTON UNIVERSITY · PI CLONINGER, C. ROBERT · 1999 to 2006
$2.7M
MOLECULAR GENETICS OF SCHIZOPHRENIAR01MH059586 · NIMH · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SILVERMAN, JEREMY M. · 1999 to 2006
$1.9M
MOLECULAR GENETICS OF SCHIZOPHRENIAR01MH061675 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI LEVINSON, DOUGLAS FREDERICK · 1999 to 2007
$1.8M
MOLECULAR GENETICS OF SCHIZOPHRENIAR01MH059587 · NIMH · EMORY UNIVERSITY · PI AMIN, FAROOQ · 1999 to 2006
$1.8M
MOLECULAR GENETICS OF SCHIZOPHRENIAR01MH059565 · NIMH · UNIVERSITY OF COLORADO DENVER · PI FREEDMAN, ROBERT · 1999 to 2006
$1.7M
MOLECULAR GENETICS OF SCHIZOPHRENIAR01MH059588 · NIMH · UNIVERSITY OF QUEENSLAND · PI MOWRY, BRYAN JOHN · 1999 to 2006
$1.4M
MOLECULAR GENETICS OF SCHIZOPHRENIAR01MH060870 · NIMH · UNIVERSITY OF CALIFORNIA IRVINE · PI BYERLEY, WILLIAM · 1999 to 2006
$1.3M
Genome-wide Association Study of SchizophreniaU01MH079470 · NIMH · STANFORD UNIVERSITY · PI LEVINSON, DOUGLAS FREDERICK · 2007 to 2009
$1.1M
MOLECULAR GENETICS OF SCHIZOPHRENIAR01MH059566 · NIMH · UNIVERSITY OF IOWA · PI BLACK, DONALD W. · 1999 to 2006
$925k
NICHD NIH HHS R01 HD041563NICHD NIH HHS R21 HD080410NIMH NIH HHS R01 MH059565NIMH NIH HHS R01 MH059566NIMH NIH HHS R01 MH059571NIMH NIH HHS R01 MH059586NIMH NIH HHS R01 MH059587NIMH NIH HHS R01 MH059588NIMH NIH HHS R01 MH060870NIMH NIH HHS R01 MH060879NIMH NIH HHS R01 MH061675NIMH NIH HHS R01 MH067257NIMH NIH HHS R01 MH081800NIMH NIH HHS U01 MH046276NIMH NIH HHS U01 MH079469NIMH NIH HHS U01 MH079470
6 · The paper itself

Abstract

Family and twin studies suggest that genes play a role in male sexual orientation. We conducted a genome-wide association study (GWAS) of male sexual orientation on a primarily European ancestry sample of 1,077 homosexual men and 1,231 heterosexual men using Affymetrix single nucleotide polymorphism (SNP) arrays. We identified several SNPs with p < 10

Indexed as

Polymorphism, Single NucleotideChromosomes, Human, Pair 13Chromosomes, Human, Pair 14FemaleGenome-Wide Association StudyHomosexuality, MaleHumansMaleMembrane ProteinsReceptors, ThyrotropinX Chromosome InactivationMembrane ProteinsReceptors, ThyrotropinSlitrk6 protein, human

Identifiers

PMID29217827
PMCPMC5721098
OpenAlexW2768974342

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.