Evidence map›Paper›PMID 29217772›Full record

ArticleThe Journal of biological chemistry2018

The intracellular immune receptor Rx1 regulates the DNA-binding activity of a Golden2-like transcription factor.

Philip D Townsend, Christopher H Dixon, Erik J Slootweg, Octavina C A Sukarta, Ally W H Yang, Timothy R Hughes, Gary J Sharples, Lars-Olof Pålsson, Frank L W Takken, Aska Goverse and 1 more

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Frontiers in plant science · 2026
    Article
  3. Article
  4. Article
  5. Advances in understanding the interaction betweenPlant signaling & behavior · 2024
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Perception of structurally distinct effectors by the integrated WRKY domain of a plant immune receptor.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Review
  16. Frontiers in plant science · 2021
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Philip D TownsendFrom the Department of Biosciences.
Christopher H DixonFrom the Department of Biosciences.
Erik J Slootwegthe Laboratory of Nematology, Department of Plant Sciences, Wageningen University, 6708 PB Wageningen, The Netherlands.
Octavina C A Sukartathe Laboratory of Nematology, Department of Plant Sciences, Wageningen University, 6708 PB Wageningen, The Netherlands.
Ally W H Yangthe Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, and.
Timothy R Hughesthe Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, and.
Gary J SharplesFrom the Department of Biosciences.
Lars-Olof PålssonDepartment of Chemistry, Durham University, South Road, Durham DH1 3LE, United Kingdom.
Frank L W TakkenMolecular Plant Pathology, Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Aska Goversethe Laboratory of Nematology, Department of Plant Sciences, Wageningen University, 6708 PB Wageningen, The Netherlands.
Martin J CannFrom the Department of Biosciences, m.j.cann@durham.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/M007405/1
6 · The paper itself

Abstract

Plant nucleotide-binding leucine-rich repeat (NLR) proteins enable the immune system to recognize and respond to pathogen attack. An early consequence of immune activation is transcriptional reprogramming, and some NLRs have been shown to act in the nucleus and interact with transcription factors. The Rx1 NLR protein of potato is further able to bind and distort double-stranded DNA. However, Rx1 host targets that support a role for Rx1 in transcriptional reprogramming at DNA are unknown. Here, we report a functional interaction between Rx1 and

Indexed as

DNAIntracellular SpaceNicotianaNLR ProteinsPlant ProteinsProtein BindingProtein DomainsTranscription FactorsDNANLR ProteinsPlant ProteinsTranscription Factors.cellular immune responseDNA-binding proteinfluorescence resonance energy transferhost-pathogen interactionNod-like receptorplant biochemistryplant defenseplant virus

Identifiers

PMID29217772
PMCPMC5836133

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.