Targeting Myocardial Energetics in the Failing Heart: Are We There Yet?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. Whole genome analyses reveal novel genes associated with chicken adaptation to tropical and frigid environments.Journal of advanced research · 2023
   Article
2. Impact of Myocardial Energy Expenditure and Diastolic Dysfunction on One Year Outcome Patients With HFpEF.Frontiers in physiology · 2022
   Article
3. Novel roles of immunometabolism and nonmyocyte metabolism in cardiac remodeling and injury.American journal of physiology. Regulatory, integrative and comparative physiology · 2020
   Review
4. Obesity, Hypertension, and Cardiac Dysfunction: Novel Roles of Immunometabolism in Macrophage Activation and Inflammation.Circulation research · 2020 · on this map
   Review
5. Human pluripotent stem cell-derived cardiomyocytes for studying energy metabolism.Biochimica et biophysica acta. Molecular cell research · 2020
   Review
6. Recently Approved and Under Investigation Drugs for Treating Patients with Heart Failure.Current cardiology reviews · 2020
   Review
7. Molecular Mechanism of the Association Between Atrial Fibrillation and Heart Failure Includes Energy Metabolic Dysregulation Due to Mitochondrial Dysfunction.Journal of cardiac failure · 2019
   Article
8. Elamipretide Improves Mitochondrial Function in the Failing Human Heart.JACC. Basic to translational science · 2019
   Article
9. Targeting Mitochondrial Function in Heart Failure: Makes Sense But Will it Work?JACC. Basic to translational science · 2019
   Article
10. Myocardial Energetics and Heart Failure: a Review of Recent Therapeutic Trials.Current heart failure reports · 2018
    Review

Corrections and comments

• Comment on
  Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide.2017

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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