Evidence map›Paper›PMID 29217753›Full record

ArticleDevelopment (Cambridge, England)2018

Wnt inhibition promotes vascular specification of embryonic cardiac progenitors.

David E Reichman, Laura Park, Limor Man, David Redmond, Kenny Chao, Richard P Harvey, Makoto M Taketo, Zev Rosenwaks, Daylon James

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Dissecting the Complexity of Early Heart Progenitor Cells.Journal of cardiovascular development and disease · 2021
    Review
  4. Article
  5. Article
  6. Stem cells and development · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

David E ReichmanCenter for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
Laura ParkCenter for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
Limor ManCenter for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
David RedmondInstitute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065, USA.
Kenny ChaoCenter for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
Richard P HarveyDevelopmental and Stem Cell Biology Laboratory, Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia.
Makoto M TaketoDepartment of Pharmacology, Graduate School of Medicine, Kyoto University, Sakyo, Kyoto 606-8501, Japan.
Zev RosenwaksCenter for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
Daylon JamesCenter for Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA djj2001@med.cornell.edu.ORCID 0000-0002-0975-2554
Cornell University · USKyoto University · JPVictor Chang Cardiac Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have demonstrated a multiphasic role for Wnt signaling during embryonic cardiogenesis and developed protocols that enrich for cardiac derivatives during

Indexed as

AnimalsEmbryo, MammalianEndothelial CellsHeartHumansMiceMice, TransgenicPluripotent Stem CellsWnt-5a ProteinWnt Signaling PathwayWnt-5a ProteinWNT5A protein, humanWnt5a protein, mouseCardiac developmentCardiac differentiationCardiovascular progenitorEndothelial differentiationHuman embryonic stem cellsMouseMyocardial infarctionMyocardial scar formationNon-canonical WntWnt5aWnt signalingWound healing

Identifiers

PMID29217753
PMCPMC5825863
OpenAlexW2782680922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.