Evidence map›Paper›PMID 29217748›Full record

ArticleAJNR. American journal of neuroradiology2018

Lower Arterial Cross-Sectional Area of Carotid and Vertebral Arteries and Higher Frequency of Secondary Neck Vessels Are Associated with Multiple Sclerosis.

P Belov, D Jakimovski, J Krawiecki, C Magnano, J Hagemeier, L Pelizzari, B Weinstock-Guttman, R Zivadinov

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

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  10. Neck Vessel Cross-Sectional Area Measured with MRI: Scan-Rescan Reproducibility for Longitudinal Evaluations.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

P BelovFrom the Buffalo Neuroimaging Analysis Center, Department of Neurology (P.B., D.J., J.K., C.M., J.H., R.Z.).ORCID 0000-0003-0961-1054
D JakimovskiFrom the Buffalo Neuroimaging Analysis Center, Department of Neurology (P.B., D.J., J.K., C.M., J.H., R.Z.).ORCID 0000-0001-7114-4958
J KrawieckiFrom the Buffalo Neuroimaging Analysis Center, Department of Neurology (P.B., D.J., J.K., C.M., J.H., R.Z.).ORCID 0000-0001-8090-1535
C MagnanoFrom the Buffalo Neuroimaging Analysis Center, Department of Neurology (P.B., D.J., J.K., C.M., J.H., R.Z.).ORCID 0000-0002-4224-4973
J HagemeierFrom the Buffalo Neuroimaging Analysis Center, Department of Neurology (P.B., D.J., J.K., C.M., J.H., R.Z.).ORCID 0000-0002-3286-5207
L PelizzariDepartment of Electronics, Information and Bioengineering (L.P.), Politecnico di Milano, Milan, Italy.ORCID 0000-0002-7563-6519
B Weinstock-GuttmanJacobs MS Center, Department of Neurology (B.W.-G.).ORCID 0000-0001-6732-151X
R ZivadinovFrom the Buffalo Neuroimaging Analysis Center, Department of Neurology (P.B., D.J., J.K., C.M., J.H., R.Z.) rzivadinov@bnac.net.ORCID 0000-0002-7799-1485
Buffalo Psychiatric Center · USDon Carlo Gnocchi Foundation · ITJacobs (United States) · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
NCATS NIH HHS UL1 TR001412
6 · The paper itself

Abstract

background and purposeArterial and neck vessel system characteristics of patients with multiple sclerosis have not been previously investigated. Therefore, the aim of this study was to examine the frequency of neck vessels and their cross-sectional areas (in square millimeters) between patients with MS and healthy controls. MATERIALS AND

methodsIn this study, 193 patients with MS and 193 age- and sex-matched healthy controls underwent 2D TOF venography at 3T. The main arterial (carotid and vertebral), venous (internal jugular), and secondary neck vessels were examined at 4 separate cervical levels (C2/3, C4, C5/6, and C7/T1). The ANCOVA adjusted for age, body mass index, smoking status, hypertension, and heart disease was used to compare the differences between patients with MS and healthy controls.

resultsAfter controlling for all confounding factors, patients with MS had significantly lower cross-sectional areas of the carotid arteries at the C2/3 (

conclusionsPatients with MS showed lower cross-sectional areas of the carotid and vertebral arteries and a higher frequency of secondary neck vessels and their cross-sectional areas compared with healthy controls.

Indexed as

AdultCarotid ArteriesCross-Sectional StudiesFemaleHumansJugular VeinsMaleMiddle AgedMultiple Sclerosis, Relapsing-RemittingNeckPhlebographyVertebral Artery

Identifiers

PMID29217748
PMCPMC5766398
OpenAlexW2773526620

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.