Evidence map›Paper›PMID 29217657›Full record

ArticleEMBO reports2018

The unique histidine in OSCP subunit of F-ATP synthase mediates inhibition of the permeability transition pore by acidic pH.

Manuela Antoniel, Kristen Jones, Salvatore Antonucci, Barbara Spolaore, Federico Fogolari, Valeria Petronilli, Valentina Giorgio, Michela Carraro, Fabio Di Lisa, Michael Forte and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in EMBO reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.

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  20. Less Severe Polymicrobial Sepsis in ConditionalInternational journal of molecular sciences · 2023
    Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Manuela AntonielConsiglio Nazionale delle Ricerche Institute of Neuroscience, Padova, Italy.
Kristen JonesVollum Institute, Oregon Health and Sciences University, Portland, OR, USA.
Salvatore AntonucciConsiglio Nazionale delle Ricerche Institute of Neuroscience, Padova, Italy.
Barbara SpolaoreDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Federico FogolariDepartment of Mathematics, Computer Sciences and Physics, University of Udine, Udine, Italy.
Valeria PetronilliConsiglio Nazionale delle Ricerche Institute of Neuroscience, Padova, Italy.
Valentina GiorgioConsiglio Nazionale delle Ricerche Institute of Neuroscience, Padova, Italy.ORCID 0000-0002-4229-3054
Michela CarraroConsiglio Nazionale delle Ricerche Institute of Neuroscience, Padova, Italy.
Fabio Di LisaConsiglio Nazionale delle Ricerche Institute of Neuroscience, Padova, Italy.
Michael ForteVollum Institute, Oregon Health and Sciences University, Portland, OR, USA.
Ildikó SzabóDepartment of Biology, University of Padova, Padova, Italy.
Giovanna LippeDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Udine, Italy giovanna.lippe@uniud.it bernardi@bio.unipd.it.ORCID 0000-0003-0042-5052
Paolo BernardiConsiglio Nazionale delle Ricerche Institute of Neuroscience, Padova, Italy giovanna.lippe@uniud.it bernardi@bio.unipd.it.ORCID 0000-0001-9187-3736
University of Padua · ITUniversity of Udine · ITVollum Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The permeability transition pore (PTP) is a Ca

Indexed as

Hydrogen-Ion ConcentrationAnimalsCalciumCalcium SignalingCattleCell LineCell Membrane PermeabilityHistidineHumansHydrolysisHypoxiaMiceMitochondria, LiverMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PoreMitochondrial Proton-Translocating ATPasesCalciumHistidineMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PoreMitochondrial Proton-Translocating ATPasesoligomycin sensitivity-conferring proteinProtein SubunitschannelF‐ATP synthasemitochondriapermeability transition

Identifiers

PMID29217657
PMCPMC5797955
OpenAlexW2771437938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.