ArticleEndocrine connections2018
Initial clinical presentation and spectrum of pheochromocytoma: a study of 94 cases from a single center.
Article in Endocrine connections, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 4 of them syntheses that pooled it.
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Who cites it
84 citing papers in PubMed, 4 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- Ectopic ACTH Syndrome Caused by Pheochromocytoma: A Case Report and Systematic Review.Endocrine, metabolic & immune disorders drug targets · 2026Pooled it
- Global epidemiology of pheochromocytoma: a systematic review and meta-analysis of observational studies.Journal of endocrinological investigation · 2025Pooled it
- Effect of surgical treatment on myocardial strain in patients with pheochromocytoma and paraganglioma: a mini-review and meta-analysis.Journal of endocrinological investigation · 2021Pooled it
- Clinical features, complications, and outcomes of exogenous and endogenous catecholamine-triggered Takotsubo syndrome: A systematic review and meta-analysis of 156 published cases.Clinical cardiology · 2020Pooled it
- Silent pheochromocytoma presenting as refractory hyperglycemia without classic adrenergic symptoms.JCEM case reports · 2026Article
- Large asymptomatic pheochromocytoma with incidental metastatic midgut carcinoid tumor.JCEM case reports · 2026Article
- Article
- Single-Cell Transcriptomic Profiling of Ectopic ACTH-Secreting Pheochromocytoma Reveals the Chromaffin Cell Origin of Ectopic Hormone Production.International journal of molecular sciences · 2026Article
- Bilateral pheochromocytoma: differences in clinical and surgical outcomes with unilateral pheochromocytomas.Endocrine · 2026Article
- Pitfalls of Adrenal Washout on CT in the Adult Population: A Pictorial Review.Diagnostics (Basel, Switzerland) · 2026Review
- Can the size of adrenal tumor impact hormonal secretion? A retrospective analysis of 170 adrenalectomies in a single center.Langenbeck's archives of surgery · 2026Article
- Symptomatic Pheochromocytoma: A Risk Model.Cancers · 2026Article
- Differences in management and outcomes between pheochromocytomas and sympathetic paragangliomas.Frontiers in endocrinology · 2026Article
- Proteinuria as an Unusual Presentation of Pheochromocytoma in Pediatric Patient With Single Kidney.Case reports in pediatrics · 2026Article
- Organizational Resources in Rare Cancer Outcomes: Survival Analysis After Surgery for Pheochromocytoma and Paraganglioma.Cancers · 2025Article
- Differences in Clinical Presentation Between Pheochromocytomas and Paragangliomas.Clinical endocrinology · 2025Article
- Prognostic markers in pheochromocytomas/paragangliomas: the role of histopathology, SDHB, MAML3 and MCM6 expression.Journal of endocrinological investigation · 2025Article
- An uncommon case of pheochromocytoma with positive biochemical workup and absence of tumor.Endocrinology, diabetes & metabolism case reports · 2025Article
- Screening of primary aldosteronism and pheochromocytoma among patients with hypertension: an Italian nationwide survey.Journal of endocrinological investigation · 2025Article
- Article
24 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWith the increasing access to imaging more pheochromocytomas are diagnosed in the workup of adrenal incidentalomas. This may have changed the occurrence of the classic presentation with hypertension and the classic triad (headaches, sweating and palpitation).
methodsWe reviewed 94 consecutive cases of pheochromocytomas. Two cases of ectopic ACTH-syndrome were subsequently excluded.
resultsOf the 92 cases included 64% had presented as an incidentaloma, 32% as a suspected pheochromocytoma and 4% had been screened because of previously diagnosed MEN2A. Those screened were youngest while those with incidentalomas were oldest. The females were more common in the incidentaloma and the screening groups, and males in the suspected pheochromocytoma group. Measurements of noradrenaline/normetanephrine levels were highest in the suspected pheocromocytoma group and lowest in the screening group. Hypertension was present in 63% of the incidentalomas, 79% of suspected pheochromocytomas and in none of the screening group. Paroxysmal symptoms were present in almost all with suspected pheochromocytoma while only in half of the other groups. The suspected pheocromocytoma group had most symptoms and the screening group least. The classic triad was present in 14% of the incidentalomas, in 28% of the suspected and in none of the screening group, while no symptoms at all was present in 12%, 0% and 25%, respectively. Pheochromocytoma crisis occurred in 5%. There was a positive correlation between tumor size vs hormone levels, and catecholamine levels vs blood pressure.
conclusionClinicians need to be aware of the modern presentation of pheochromocytomas since early identification can be life-saving.
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