ArticleThe Journal of pharmacology and experimental therapeutics2018
Inhibition of Cocaine and 3,4-Methylenedioxypyrovalerone (MDPV) Self-Administration by Lorcaserin Is Mediated by 5-HT2C Receptors in Rats.
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Article in The Journal of pharmacology and experimental therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- The serotonin-2C agonist Lorcaserin delays intravenous choice and modifies the subjective and cardiovascular effects of cocaine: A randomized, controlled human laboratory study.Pharmacology, biochemistry, and behavior · 2019Trial
- It's not all DAT: harnessing the potential of organic cation transporter 3 inhibition to selectively attenuate amphetamine reinforcement and dopamine release.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- 96-h methamphetamine self-administration elicits striatal dopamine depletion in male and female rats: a model of binge-like use.Psychopharmacology · 2026Article
- Chronic Cocaine Use and Parkinson's Disease: An Interpretative Model.International journal of environmental research and public health · 2024Article
- Interactions between lorcaserin and opioids: Ventilation and food-versus-drug choice.Pharmacology, biochemistry, and behavior · 2024Article
- Cocaine hydrochloride, cocaine methiodide and methylenedioxypyrovalerone (MDPV) cause distinct alterations in the structure and composition of the gut microbiota.Scientific reports · 2023Article
- 3,4-Methylenedioxypyrovalerone High-Responder Phenotype as a Tool to Evaluate Candidate Medications for Stimulant Use Disorder.The Journal of pharmacology and experimental therapeutics · 2023Article
- Evaluation of the 5-HTPharmacological reports : PR · 2023Article
- Converging vulnerability factors for compulsive food and drug use.Neuropharmacology · 2021Review
- 3,4-Methylenedioxypyrovalerone: Neuropharmacological Impact of a Designer Stimulant of Abuse on Monoamine Transporters.The Journal of pharmacology and experimental therapeutics · 2020Article
- Self-administration of the synthetic cathinones 3,4-methylenedioxypyrovalerone (MDPV) and α-pyrrolidinopentiophenone (α-PVP) in rhesus monkeys.Psychopharmacology · 2019Article
- Repeated administration of synthetic cathinone 3,4-methylenedioxypyrovalerone persistently increases impulsive choice in rats.Behavioural pharmacology · 2019Article
- Behavioral economic analysis of the reinforcing effects of "bath salts" mixtures: studies with MDPV, methylone, and caffeine in male Sprague-Dawley rats.Psychopharmacology · 2019Article
- Effects of lorcaserin on reinstatement of responding previously maintained by cocaine or remifentanil in rhesus monkeys.Experimental and clinical psychopharmacology · 2019Article
- Lorcaserin decreases the reinforcing effects of heroin, but not food, in rhesus monkeys.European journal of pharmacology · 2018Article
- DARK Classics in Chemical Neuroscience: Cathinone-Derived Psychostimulants.ACS chemical neuroscience · 2018Review
- Effects of lorcaserin and buspirone, administered alone and as a mixture, on cocaine self-administration in male and female rhesus monkeys.Experimental and clinical psychopharmacology · 2018Article
- Challenging obesity, diabetes, and addiction: the potential of lorcaserin extended release.Diabetes, metabolic syndrome and obesity : targets and therapy · 2018Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Brenda M GannonDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas (B.M.G., G.T.C.); South Texas Veterans Health Care System, San Antonio, Texas (G.T.C.); and Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland (A.S., K.C.R.).
Agnieszka SulimaDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas (B.M.G., G.T.C.); South Texas Veterans Health Care System, San Antonio, Texas (G.T.C.); and Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland (A.S., K.C.R.).
Kenner C RiceDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas (B.M.G., G.T.C.); South Texas Veterans Health Care System, San Antonio, Texas (G.T.C.); and Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland (A.S., K.C.R.).
Gregory T CollinsDepartment of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas (B.M.G., G.T.C.); South Texas Veterans Health Care System, San Antonio, Texas (G.T.C.); and Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland (A.S., K.C.R.) CollinsG@uthscsa.edu.
National Institute on Alcohol Abuse and Alcoholism · USSouth Texas Veterans Health Care System · US
Funding
Training in Drug Abuse Research: Behavior and NeurobiologyT32DA031115 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHARLES P FRANCE · 2011 to 2026
$5.2MMedicinal Chemistry of Drugs Acting on Biogenic Amine ReceptorsZIADA000532 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI RICE, KENNER · 2009 to 2020
$4.5MBath Salts: Abuse-related and Toxic EffectsR01DA039146 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Gregory Collins · 2015 to 2026
$4.0MNIDA NIH HHS R01 DA039146NIDA NIH HHS T32 DA031115
Abstract
Lorcaserin is a serotonin (5-HT)
Indexed as
AnimalsBenzazepinesBenzodioxolesCocaineDose-Response Relationship, DrugMalePyrrolidinesRatsRats, Sprague-DawleyReceptor, Serotonin, 5-HT2CReinforcement, PsychologySelf AdministrationSerotonin 5-HT2 Receptor AgonistsSynthetic CathinoneBenzazepinesBenzodioxolesCocainelorcaserinPyrrolidinesReceptor, Serotonin, 5-HT2CSerotonin 5-HT2 Receptor AgonistsSynthetic Cathinone
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.