ReviewAmerican journal of ophthalmology2018
Endophthalmitis: Then and Now.
Review in American journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.
- Early vitrectomy for exogenous endophthalmitis following surgery.The Cochrane database of systematic reviews · 2022Pooled it
- Lessons Learnt From 25 Years of Endophthalmitis: Causes, Microbiology and Visual Outcome Trends.Clinical & experimental ophthalmology · 2026Article
- A second occurrence of intravitreal injection-associated endophthalmitis 2 years apart.American journal of ophthalmology case reports · 2026Article
- Incidence of post-traumatic endophthalmitis following repaired open globe injury: impact of prophylactic intracameral moxifloxacin.Eye (London, England) · 2026Article
- Areas of uncertainty in endophthalmitis care.World journal of clinical cases · 2026Review
- Comparative incidence of endophthalmitis after intravitreal dexamethasone implant versus anti-VEGF injections: a retrospective study.International journal of retina and vitreous · 2026Article
- A systemic pharmacovigilance assessment of ophthalmic atropine: signal detection and clinical prioritization from the FAERS database.Frontiers in medicine · 2026Article
- Complete and Early Vitrectomy for Sterile Endophthalmitis After Bevacizumab: A Case Series.Cureus · 2025Article
- Article
- Endophthalmitis following inadvertent intravitreal injection of botulinum toxin: a case report and literature review.BMC ophthalmology · 2025Review
- Clinical performance of nanopore targeted sequencing for diagnosing endophthalmitis.BMC microbiology · 2025Article
- A favorable prognosis case of posttraumatic endophthalmitis possibly from the protective effect of previously implanted implantable collamer lens (ICLs).American journal of ophthalmology case reports · 2025Article
- Metabolomic Profiling of Ocular Fluid Identifies Host Response Factors for Risk Stratification in Bacterial Endophthalmitis.Investigative ophthalmology & visual science · 2025Article
- Comparison of Endophthalmitis Rates Between Prefilled Syringes and Standard Vials in Aflibercept Intravitreal Injections: A Retrospective Study in Japan.Journal of clinical medicine · 2025Article
- Controversies in the management of endophthalmitis: a 5-year retrospective cohort study.Journal of ophthalmic inflammation and infection · 2025Article
- Systemic and localized infections in humans caused by Paenibacillus: a case report and literature review.BMC ophthalmology · 2025Review
- Postoperative endophthalmitis treatment with antibiotics associated or not with pars plana vitrectomy: a randomized clinical trial.International journal of retina and vitreous · 2025Article
- Article
- Rapid, multiplex and automated detection of bacteria and fungi in endophthalmitis via a microfluidic real-time pcr system.Journal of ophthalmic inflammation and infection · 2024Article
- Efficacy of 1% Povidone-Iodine in the Treatment of Anterior Blepharitis-Randomized Single-Center Controlled Trial.Journal of clinical medicine · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo report historically evolving strategies (then and now) in prevention and management of endophthalmitis.
designA perspective on relevant topics in the prophylaxis and management of endophthalmitis.
methodsThis is an author-selected review of studies leading to changes in strategies for endophthalmitis management over the last 100 years.
resultsThe current perspective discusses the trends and strategies over the past century. Historically, 3 endophthalmitis time-periods have existed and include the pre-antimicrobial era, the predominantly systemic antimicrobial era, and the current intravitreal antimicrobial era. The management of endophthalmitis from different etiologies, including endogenous, postinjection, post-cataract surgery, and other anterior segment-related (eg, post-penetrating keratoplasty), bleb-associated, glaucoma drainage device-associated, and open globe injury-associated, are discussed. Specific etiologies may predict most common microbial causes and may guide differing management strategies. Pars plana vitrectomy offers theoretical advantages but is generally reserved for patients with more advanced disease.
conclusionsDespite advances over the past 100 years, endophthalmitis is an important sight-threatening complication. Timely management with the appropriate use of antimicrobial agents may optimize visual outcomes.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.