Evidence map›Paper›PMID 29217133›Full record

ArticleThe Journal of allergy and clinical immunology2018

Prostaglandin E

Jovana Maric, Avinash Ravindran, Luca Mazzurana, Åsa K Björklund, Aline Van Acker, Anna Rao, Danielle Friberg, Sven-Erik Dahlén, Akos Heinemann, Viktoria Konya and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 137 citations in OpenAlex.

  1. Review
  2. Article
  3. Group 2 innate lymphoid cells: Where are we 15 years out?The Journal of allergy and clinical immunology · 2026
    Review
  4. Article
  5. Asthma endotypes and theratypes.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. A CD4Immunity · 2025
    Article
  10. Review
  11. New insights into the mechanisms of aspirin-exacerbated respiratory disease.Current opinion in allergy and clinical immunology · 2025
    Review
  12. Review
  13. Low Prostaglandin EJournal of clinical medicine · 2024
    Review
  14. Review
  15. Article
  16. Article
  17. Mast Cells in Aspirin-Exacerbated Respiratory Disease.Current allergy and asthma reports · 2024
    Review
  18. Review
  19. Activation of the PGEFrontiers in immunology · 2024
    Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jovana MaricInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Avinash RavindranImmunology and Allergy Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Luca MazzuranaCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Åsa K BjörklundScience for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.
Aline Van AckerCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Anna RaoCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Danielle FribergDepartment of Oto-Rhino-Laryngology, Karolinska University Hospital and CLINTEC, Karolinska Institutet, Stockholm, Sweden.
Sven-Erik DahlénExperimental Asthma and Allergy Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Akos HeinemannInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria.
Viktoria KonyaInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Graz, Austria; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden. Electronic address: viktoria.konya@medunigraz.at.
Jenny MjösbergCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden. Electronic address: jenny.mjosberg@ki.se.
Karolinska Institutet · SEMedical University of Graz · ATKarolinska University Hospital · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGroup 2 innate lymphoid cells (ILC2s) are involved in the initial phase of type 2 inflammation and can amplify allergic immune responses by orchestrating other type 2 immune cells. Prostaglandin (PG) E

objectiveWe set out to investigate how PGE

methodsThe effects of PGE

resultsPGE

conclusionOur findings reveal that PGE

Indexed as

Cells, CulturedCytokinesDinoprostoneGATA3 Transcription FactorGene Expression RegulationHumansImmunity, InnateInflammationLymphocytesReceptors, Prostaglandin ECytokinesDinoprostoneGATA3 Transcription FactorReceptors, Prostaglandin EallergyE-type prostanoid receptor 2E-type prostanoid receptor 4ILC2prostaglandin E(2)

Identifiers

PMID29217133
PMCPMC5929462
OpenAlexW2774252423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.