ArticleThe Journal of pediatrics2018
Proinflammatory Diets during Pregnancy and Neonatal Adiposity in the Healthy Start Study.
Article in The Journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02273297 (Exploring the Fuel-mediated Programming of Neonatal Growth), which is not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exploring the Fuel-mediated Programming of Neonatal Growth
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Associations Between Late Pregnancy Dietary Inflammatory Index (DII) and Offspring Bone Mass: A Meta-Analysis of the Southampton Women's Survey (SWS) and the Avon Longitudinal Study of Parents and Children (ALSPAC).Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022Pooled it
- Associations between Maternal Dietary Patterns and Perinatal Outcomes: A Systematic Review and Meta-Analysis of Cohort Studies.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Associations between Dietary Patterns and Inflammatory Markers during Pregnancy: A Systematic Review.Nutrients · 2021Pooled it
- Trial
- The association of inflammatory potential of diet and height status among adolescent girls: a cross-sectional study in the west of Iran in 2018-2019.BMC women's health · 2026Article
- Cross-Generational Integration of Exercise and Nutritional Encoding in Offspring Adipose Genomics.International journal of molecular sciences · 2026Review
- Maternal dietary inflammatory index during pregnancy and the risk of offspring allergic disease.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
- New Frontiers: Umbilical Cord Mesenchymal Stem Cells Uncover Developmental Roots and Biological Underpinnings of Obesity Susceptibility.Current obesity reports · 2025Review
- Developmental Contributions to Obesity: Nutritional Exposures in the First Thousand Days.Gastroenterology clinics of North America · 2023Review
- Association Between Infants Anthropometric Outcomes With Maternal AHEI-P and DII Scores.Clinical nutrition research · 2023Article
- Maternal Diet Quality During Pregnancy and Offspring Hepatic Fat in Early Childhood: The Healthy Start Study.The Journal of nutrition · 2023Article
- Neighborhood Walkability, Historical Redlining, and Childhood Obesity in Denver, Colorado.Journal of urban health : bulletin of the New York Academy of Medicine · 2023Article
- Anti-inflammatory diets reduce the risk of excessive gestational weight gain in urban South Africans from the Soweto First 1000-Day Study (S1000).European journal of nutrition · 2022Article
- Maternal mindful eating as a target for improving metabolic outcomes in pregnant women with obesity.Frontiers in bioscience (Landmark edition) · 2021Observational
- Examining Associations Between Dietary Inflammatory Index in Pregnancy, Pro-inflammatory Cytokine and Chemokine Levels at Birth, and Offspring Asthma and/or Wheeze by Age 4 Years.Journal of the Academy of Nutrition and Dietetics · 2021Article
- Maternal Dietary Quality and Dietary Inflammation Associations with Offspring Growth, Placental Development, and DNA Methylation.Nutrients · 2021Review
- Effects of Dietary Patterns during Pregnancy on Preterm Birth: A Birth Cohort Study in Shanghai.Nutrients · 2021Article
- Understanding the value of dietary indices prior to research application.BMC medicine · 2021Article
- Incidence and timing of offspring asthma, wheeze, allergic rhinitis, atopic dermatitis, and food allergy and association with maternal history of asthma and allergic rhinitis.The World Allergy Organization journal · 2021Article
- Article
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8 authors.
Funding
Abstract
objectiveTo evaluate the association between dietary inflammatory index (DII) scores during pregnancy and neonatal adiposity. STUDY
designThe analysis included 1078 mother-neonate pairs in Healthy Start, a prospective prebirth cohort. Diet was assessed using repeated 24-hour dietary recalls. DII scores were obtained by summing nutrient intakes, which were standardized to global means and multiplied by inflammatory effect scores. Air displacement plethysmography measured fat mass and fat-free mass within 72 hours of birth. Linear and logistic models evaluated the associations of DII scores with birth weight, fat mass, fat-free mass, and percent fat mass, and with categorical outcomes of small- and large-for-gestational age. We tested for interactions with prepregnancy BMI and gestational weight gain.
resultsThe interaction between prepregnancy BMI and DII was statistically significant for birth weight, neonatal fat mass, and neonatal percent fat mass. Among neonates born to obese women, each 1-unit increase in DII was associated with increased birth weight (53 g; 95% CI, 20, 87), fat mass (20 g; 95% CI, 7-33), and percent fat mass (0.5%; 95% CI, 0.2-0.8). No interaction was detected for small- and large-for-gestational age. Each 1-unit increase in DII score was associated a 40% increase in odds of a large-for-gestational age neonate (1.4; 95% CI, 1.0-2.0; P = .04), but not a small-for-gestational age neonate (1.0; 95% CI, 0.8-1.2; P = .80). There was no evidence of an interaction with gestational weight gain.
conclusionsOur findings support the hypothesis that an increased inflammatory milieu during pregnancy may be a risk factor for neonatal adiposity.
trial registrationClinicaltrials.gov: NCT02273297.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.