Evidence map›Paper›PMID 29217059›Full record

ReviewOtolaryngologic clinics of North America2018

New Frontiers in Our Understanding of Lymphatic Malformations of the Head and Neck: Natural History and Basic Research.

Jonathan A Perkins

Abstract readReview
In one paragraph

Review in Otolaryngologic clinics of North America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. [Analysis of MRI and clinical characteristics for pediatric head, neck, and facial lymphatic malformations].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Article
  4. Treatments and Outcomes of Pediatric Head and Neck Lymphatic Malformations: A 20-Year Single Institution Experience.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  5. New Insights into Cervicofacial Vascular Anomalies.Journal of clinical medicine · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Pediatric vascular anomalies with airway compromise.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2022
    Review
  11. Article
  12. Article
  13. Long-term symptom control following resection of cervical lymphatic malformations: a case series.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Medical Management of Vascular Anomalies.Current treatment options in pediatrics · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jonathan A PerkinsOtolaryngology/Head and Neck Surgery, University of Washington School of Medicine, 1959 Pacific Avenue NE, Box 366515, Seattle, WA 98195, USA; Vascular Anomalies Program, Seattle Children's Hospital, 4800 Sand Point Way Northeast, Seattle, WA 98105, USA. Electronic address: jonathan.perkins@seattlechildrens.org.

Funding

Mosaic: post-zygotic mutations in vascular malformationsR01HL130996 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI BENNETT, JAMES T · 2016 to 2024
$7.5M
Megalencephaly and segmental brain overgrowth in humansR01NS092772 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI MILLEN, KATHLEEN JOYCE · 2015 to 2019
$3.3M
NHLBI NIH HHS R01 HL130996NINDS NIH HHS R01 NS092772
6 · The paper itself

Abstract

The future of head and neck lymphatic malformation (HNLM) evaluation and treatment is changing because of 2 decades of clinical research and recent basic science investigation. Basic science investigation using cellular biology and molecular genetics has revealed the genetic cause of some HNLMs, which has created the possibility of medical treatment specific to HNLM. This article summarizes the clinical and basic science research that will likely influence the future of HNLM assessment and treatment.

Indexed as

Biomedical ResearchCapillariesChildFemaleHead and Neck NeoplasmsHumansLymphangiomaNatural HistoryPregnancyPrenatal DiagnosisVascular MalformationsBasic researchHead and neckLymphatic malformationsNatural history

Identifiers

PMID29217059
PMCPMC5726598

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.