Evidence map›Paper›PMID 29216852›Full record

ArticleBMC pulmonary medicine2017

Access to affordable medicines and diagnostic tests for asthma and COPD in sub Saharan Africa: the Ugandan perspective.

Davis Kibirige, Leaticia Kampiire, David Atuhe, Raymond Mwebaze, Winceslaus Katagira, Winters Muttamba, Rebecca Nantanda, William Worodria, Bruce Kirenga

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
18.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Performance of alternative COPD case-finding tools: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Davis KibirigeDepartment of Medicine, Uganda Martyrs Hospital Lubaga, P.O. BOX 7146, Kampala, Uganda. kibirigedavis@gmail.com.
Leaticia KampiireInfectious Disease Research Collaboration (IDRC), Kampala, Uganda.
David AtuheDepartment of Medicine, Case hospital Kampala, Kampala, Uganda.
Raymond MwebazeDepartment of Medicine, St. Francis hospital Nsambya, Kampala, Uganda.
Winceslaus KatagiraMakerere Lung Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Winters MuttambaMakerere Lung Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Rebecca NantandaMakerere Lung Institute, Makerere University College of Health Sciences, Kampala, Uganda.
William WorodriaDivision of Pulmonology, Mulago National Referral and Teaching hospital, Kampala, Uganda.
Bruce KirengaMakerere Lung Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Makerere University · UGNsambya Hospital · UGInfectious Diseases Research Collaboration · UGMulago Hospital · UGRubaga Hospital · UG

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Inflammation, Aging, Microbes, Obstructive Lung Disease and Diffusion Abnormalities (I AM OLD-DA) Study - Diversity SupplementR01HL128156 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, LAURENCE, HUNT, PETER W · 2015 to 2024
$7.1M
FIC NIH HHS D43 TW010540NHLBI NIH HHS R01 HL128156
6 · The paper itself

Abstract

backgroundEquitable access to affordable medicines and diagnostic tests is an integral component of optimal clinical care of patients with asthma and chronic obstructive pulmonary disease (COPD). In Uganda, we lack contemporary data about the availability, cost and affordability of medicines and diagnostic tests essential in asthma and COPD management.

methodsData on the availability, cost and affordability of 17 medicines and 2 diagnostic tests essential in asthma and COPD management were collected from 22 public hospitals, 23 private and 85 private pharmacies. The percentage of the available medicines and diagnostic tests, the median retail price of the lowest priced generic brand and affordability in terms of the number of days' wages it would cost the least paid public servant were analysed.

resultsThe availability of inhaled short acting beta agonists (SABA), oral leukotriene receptor antagonists (LTRA), inhaled LABA-ICS combinations and inhaled corticosteroids (ICS) in all the study sites was 75%, 60.8%, 46.9% and 45.4% respectively. None of the study sites had inhaled long acting anti muscarinic agents (LAMA) and inhaled long acting beta agonist (LABA)-LAMA combinations. Spirometry and peak flow-metry as diagnostic tests were available in 24.4% and 6.7% of the study sites respectively. Affordability ranged from 2.2 days' wages for inhaled salbutamol to 17.1 days' wages for formoterol/budesonide inhalers and 27.8 days' wages for spirometry.

conclusionMedicines and diagnostic tests essential in asthma and COPD care are not widely available in Uganda and remain largely unaffordable. Strategies to improve access to affordable asthma and COPD medicines and diagnostic tests should be implemented in Uganda.

Indexed as

Health Services AccessibilityAdministration, InhalationAdrenal Cortex HormonesAdrenergic beta-AgonistsAlbuterolAnti-Asthmatic AgentsAsthmaBudesonide, Formoterol Fumarate Drug CombinationDiagnostic Techniques, Respiratory SystemDrug CombinationsDrug CostsFluticasone-Salmeterol Drug CombinationHumansLeukotriene AntagonistsMuscarinic AntagonistsPulmonary Disease, Chronic ObstructiveAdrenal Cortex HormonesAdrenergic beta-AgonistsAlbuterolAnti-Asthmatic AgentsBudesonide, Formoterol Fumarate Drug CombinationDrug CombinationsFluticasone-Salmeterol Drug CombinationLeukotriene AntagonistsMuscarinic AntagonistsAccessAsthmaCOPDDiagnostic testsMedicinesSub Saharan AfricaUganda

Identifiers

PMID29216852
PMCPMC5721472
OpenAlexW2771211631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.