ArticlePloS one2017
Composition and variation of respiratory microbiota in healthy military personnel.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- WORKbiota: A Systematic Review about the Effects of Occupational Exposure on Microbiota and Workers' Health.International journal of environmental research and public health · 2022Pooled it
- Oropharyngeal microbiome profiling and its association with age and heart failure in the elderly population from the northernmost province of China.Microbiology spectrum · 2024Article
- The Role of the Microbiome in Allergy, Asthma, and Occupational Lung Disease.Current allergy and asthma reports · 2024Review
- Comparison of the upper and lower airway microbiome in early postoperative lung transplant recipients.Microbiology spectrum · 2024Article
- The nasopharyngeal microbiome in COVID-19.Emerging microbes & infections · 2023Article
- Deep nasal sinus cavity microbiota dysbiosis in Parkinson's disease.NPJ Parkinson's disease · 2021Article
- Nasopharyngeal Microbiota in SARS-CoV-2 Positive and Negative Patients.Biological procedures online · 2021Article
- Nasal Microbiota and Infectious Complications After Elective Surgical Procedures.JAMA network open · 2021Article
- Article
- Association of chronic rhinosinusitis with high microbiome dissimilarity among different patients and within individuals over time.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2020Article
- Oropharyngeal microbiome of a college population following a meningococcal disease outbreak.Scientific reports · 2020Article
- The use of Unmanned Aerial Vehicles (UAVs) to sample the blow microbiome of small cetaceans.PloS one · 2020Article
- Evaluation of a stepwise approach using microbiota analysis, species-specific qPCRs and culture for the diagnosis of lower respiratory tract infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Article
- Impact of occupational exposure on human microbiota.Current opinion in allergy and clinical immunology · 2019Review
- Pediatric asthma comprises different phenotypic clusters with unique nasal microbiotas.Microbiome · 2018Article
- Comparison of Oropharyngeal Microbiota in Healthy Piglets and Piglets With Respiratory Disease.Frontiers in microbiology · 2018Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Certain occupational and geographical exposures have been associated with an increased risk of lung disease. As a baseline for future studies, we sought to characterize the upper respiratory microbiomes of healthy military personnel in a garrison environment. Nasal, oropharyngeal, and nasopharyngeal swabs were collected from 50 healthy active duty volunteers eight times over the course of one year (1107 swabs, completion rate = 92.25%) and subjected to pyrosequencing of the V1-V3 region of 16S rDNA. Respiratory bacterial taxa were characterized at the genus level, using QIIME 1.8 and the Ribosomal Database Project classifier. High levels of Staphylococcus, Corynebacterium, and Propionibacterium were observed among both nasal and nasopharyngeal microbiota, comprising more than 75% of all operational taxonomical units (OTUs). In contrast, Streptococcus was the sole dominant bacterial genus (approximately 50% of all OTUs) in the oropharynx. The average bacterial diversity was greater in the oropharynx than in the nasal or nasopharyngeal region at all time points. Diversity analysis indicated a significant overlap between nasal and nasopharyngeal samples, whereas oropharyngeal samples formed a cluster distinct from these two regions. The study produced a large set of pyrosequencing data on the V1-V3 region of bacterial 16S rDNA for the respiratory microbiomes of healthy active duty Service Members. Pre-processing of sequencing reads showed good data quality. The derived microbiome profiles were consistent both internally and with previous reports, suggesting their utility for further analyses and association studies based on sequence and demographic data.
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