Evidence map›Paper›PMID 29215871›Full record

ArticleAnalytical chemistry2018

MPA Portable: A Stand-Alone Software Package for Analyzing Metaproteome Samples on the Go.

Thilo Muth, Fabian Kohrs, Robert Heyer, Dirk Benndorf, Erdmann Rapp, Udo Reichl, Lennart Martens, Bernhard Y Renard

Abstract read
In one paragraph

Article in Analytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Bioinformatic Workflows for Metaproteomics.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Novel Bioinformatics Strategies Driving Dynamic Metaproteomic Studies.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  16. Review
  17. Review
  18. Microbiota and Ocular Diseases.Frontiers in cellular and infection microbiology · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thilo MuthBioinformatics Unit (MF 1), Department for Methods Development and Research Infrastructure, Robert Koch Institute , 13353 Berlin, Germany.ORCID 0000-0001-8304-2684
Fabian KohrsBioprocess Engineering, Otto von Guericke University Magdeburg , 39106 Magdeburg, Germany.
Robert HeyerBioprocess Engineering, Otto von Guericke University Magdeburg , 39106 Magdeburg, Germany.
Dirk BenndorfBioprocess Engineering, Otto von Guericke University Magdeburg , 39106 Magdeburg, Germany.
Erdmann RappMax Planck Institute for Dynamics of Complex Technical Systems , Bioprocess Engineering, 39106 Magdeburg, Germany.
Udo ReichlBioprocess Engineering, Otto von Guericke University Magdeburg , 39106 Magdeburg, Germany.
Lennart MartensDepartment of Biochemistry, Ghent University , 9000 Ghent, Belgium.ORCID 0000-0003-4277-658X
Bernhard Y RenardBioinformatics Unit (MF 1), Department for Methods Development and Research Infrastructure, Robert Koch Institute , 13353 Berlin, Germany.

Funding

Expanding multiplexed kinase biosensor analysis to SWATH-MS (Part 2 of 2)U24CA199347 · NCI · UNIVERSITY OF MINNESOTA · PI GRIFFIN, TIMOTHY J. · 2016 to 2019
$2.4M
NCI NIH HHS U24 CA199347
6 · The paper itself

Abstract

Metaproteomics, the mass spectrometry-based analysis of proteins from multispecies samples faces severe challenges concerning data analysis and results interpretation. To overcome these shortcomings, we here introduce the MetaProteomeAnalyzer (MPA) Portable software. In contrast to the original server-based MPA application, this newly developed tool no longer requires computational expertise for installation and is now independent of any relational database system. In addition, MPA Portable now supports state-of-the-art database search engines and a convenient command line interface for high-performance data processing tasks. While search engine results can easily be combined to increase the protein identification yield, an additional two-step workflow is implemented to provide sufficient analysis resolution for further postprocessing steps, such as protein grouping as well as taxonomic and functional annotation. Our new application has been developed with a focus on intuitive usability, adherence to data standards, and adaptation to Web-based workflow platforms. The open source software package can be found at https://github.com/compomics/meta-proteome-analyzer .

Indexed as

SoftwareAlgorithmsMass SpectrometryProteomeProteomicsProteome

Identifiers

PMID29215871
PMCPMC5757220

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.