Evidence map›Paper›PMID 29215790›Full record

ArticleMolecular oncology2018

Inhibition of fucosylation in human invasive ductal carcinoma reduces E-selectin ligand expression, cell proliferation, and ERK1/2 and p38 MAPK activation.

Mylène A Carrascal, Mariana Silva, José S Ramalho, Cláudia Pen, Manuela Martins, Carlota Pascoal, Constança Amaral, Isabel Serrano, Maria José Oliveira, Robert Sackstein and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecular oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. E-selectin in vascular pathophysiology.Frontiers in immunology · 2024
    Review
  12. Article
  13. Core fucosylation and its roles in gastrointestinal glycoimmunology.World journal of gastrointestinal oncology · 2023
    Review
  14. Sialyl LewisCancers · 2023
    Article
  15. Bone marrow vasculature advancedFrontiers in cardiovascular medicine · 2023
    Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Mylène A CarrascalUCIBIO, Departamento Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Portugal.
Mariana SilvaCEDOC, Chronic Diseases Research Center, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Portugal.
José S RamalhoCEDOC, Chronic Diseases Research Center, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Portugal.
Cláudia PenCentro Hospitalar de Lisboa Central, EPE - Serviço de Anatomia Patológica, Lisbon, Portugal.
Manuela MartinsCentro Hospitalar de Lisboa Central, EPE - Serviço de Anatomia Patológica, Lisbon, Portugal.
Carlota PascoalUCIBIO, Departamento Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Portugal.
Constança AmaralUCIBIO, Departamento Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Portugal.
Isabel SerranoHospital de Cascais, Portugal.
Maria José OliveiraNew Therapies Group, INEB-Institute for Biomedical Engineering, Porto, Portugal.
Robert SacksteinDepartments of Dermatology and Medicine, Brigham & Women's Hospital, Boston, MA, USA.
Paula A VideiraUCIBIO, Departamento Ciências da Vida, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Portugal.ORCID 0000-0001-5987-2485
Universidade Nova de Lisboa · PTBrigham and Women's Hospital · USUnidade Local de Saúde de São José · PTi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PT

Funding

REGULATION OF LACTOSAMINYL GLYCAN BIOSYNTHESIS IN HEMATOPOIETIC CELLSP01HL107146 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LAU, JOSEPH TY · 2011 to 2017
$17.7M
NHLBI NIH HHS P01 HL107146
6 · The paper itself

Abstract

Breast cancer tissue overexpresses fucosylated glycans, such as sialyl-Lewis X/A (sLe

Indexed as

AdultAgedBreast NeoplasmsCarcinoma, Ductal, BreastCell AdhesionCell Line, TumorCell ProliferationE-SelectinFemaleFucoseFucosyltransferasesHumansLigandsMAP Kinase Signaling SystemMiddle AgedNeoplasm InvasivenessE-SelectinFucoseFucosyltransferasesLigandsOligosaccharidesp38 Mitogen-Activated Protein KinasesSELE protein, humanSialyl Lewis X Antigenbreast cancercell migrationfucosylationproliferationsialyl-Lewis X/A

Identifiers

PMID29215790
PMCPMC5928367
OpenAlexW2772853164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.