ArticleJournal of cellular physiology2018
Simple kinetic model of mitochondrial swelling in cardiac cells.
Article in Journal of cellular physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 49 citations in OpenAlex.
- Cerebrospinal Fluid From Patients With HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) With Rapid Evolution Affects Mitochondrial DNA Transcription and Network Organization in Human Glioblastoma Cells.Journal of medical virology · 2025Article
- Spaceflight-induced contractile and mitochondrial dysfunction in an automated heart-on-a-chip platform.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Role of mitochondria in neonatal hypoxic-ischemic encephalopathy.Histology and histopathology · 2024Review
- Article
- The Role of Swelling in the Regulation of OPA1-Mediated Mitochondrial Function in the Heart In Vitro.Cells · 2023Article
- Mitochondrial Volume Regulation and Swelling Mechanisms in Cardiomyocytes.Antioxidants (Basel, Switzerland) · 2023Review
- Neuroprotective and Antioxidant Role of Oxotremorine-M, a Non-selective Muscarinic Acetylcholine Receptors Agonist, in a Cellular Model of Alzheimer Disease.Cellular and molecular neurobiology · 2023Article
- Crosstalk between adenine nucleotide transporter and mitochondrial swelling: experimental and computational approaches.Cell biology and toxicology · 2023Article
- Mitochondrial decline in the ageing old world primate retina: Little evidence for difference between the centre and periphery.PloS one · 2023Article
- Mitochondria Dysfunction and Cell Apoptosis Limit Resistance of Nile Tilapia (Animals : an open access journal from MDPI · 2022Article
- Calreticulin Shortage Results in Disturbance of Calcium Storage, Mitochondrial Disease, and Kidney Injury.Cells · 2022Article
- New Neuroprotective Effect of Lemon IntegroPectin on Neuronal Cellular Model.Antioxidants (Basel, Switzerland) · 2021Article
- Isolation of Mitochondria From Fresh Mice Lung Tissue.Frontiers in physiology · 2021Article
- Increased Reactive Oxygen Species and Distinct Oxidative Damage in Resveratrol-suppressed Glioblastoma Cells.Journal of Cancer · 2021Article
- Acetaminophen-induced hepatotoxicity: different mechanisms of acetaminophen-induced ferroptosis and mitochondrial damage.Archives of toxicology · 2020Article
- Regular Intake of Pistachio Mitigates the Deleterious Effects of a High Fat-Diet in the Brain of Obese Mice.Antioxidants (Basel, Switzerland) · 2020Article
- Dual dynamics of mitochondrial permeability transition pore opening.Scientific reports · 2020Article
- Human Single-chain Variable Fragments NeutralizeFrontiers in microbiology · 2020Article
- In silico simulation of reversible and irreversible swelling of mitochondria: The role of membrane rigidity.Mitochondrion · 2020Article
- Cytoplasmic and Mitochondrial Calcium Signaling: A Two-Way Relationship.Cold Spring Harbor perspectives in biology · 2019Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Mitochondria play an important role in both cell survival and cell death. In response to oxidative stress, they undergo opening of non-selective permeability transition pores (PTP) in the inner mitochondrial membrane. Sustained PTP opening triggers mitochondrial swelling due to increased colloidal osmotic pressure in the matrix accompanied by mitochondrial membrane depolarization and ATP hydrolysis. Mitochondrial swelling is the major factor leading to mitochondria-mediated cell death through both apoptosis and necrosis. Hence, precise estimation of the threshold parameters of the transition of reversible swelling to irreversible swelling is important for understanding the mechanisms of PTP-mediated cell death as well as for the development of new therapeutic approaches targeting the mitochondria under pathological conditions. In this study, we designed a simple kinetic model of the Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.