Evidence map›Paper›PMID 29215579›Full record

ReviewMarine drugs2017

The Potential of Indonesian Heterobranchs Found around Bunaken Island for the Production of Bioactive Compounds.

Katja M Fisch, Cora Hertzer, Nils Böhringer, Zerlina G Wuisan, Dorothee Schillo, Robert Bara, Fontje Kaligis, Heike Wägele, Gabriele M König, Till F Schäberle

Abstract readReview
In one paragraph

Review in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Antibacterial scalarane fromBeilstein journal of organic chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katja M FischInstitute for Insect Biotechnology, Justus-Liebig-University Giessen, 35392 Giessen, Germany. Katja.M.Fisch@agrar.uni-giessen.de.
Cora HertzerInstitute for Pharmaceutical Biology, Rheinische Friedrich-Wilhelms-University Bonn, 53115 Bonn, Germany. s6coherz@uni-bonn.de.
Nils BöhringerInstitute for Insect Biotechnology, Justus-Liebig-University Giessen, 35392 Giessen, Germany. nils.boehringer@uni-bonn.de.
Zerlina G WuisanInstitute for Insect Biotechnology, Justus-Liebig-University Giessen, 35392 Giessen, Germany. Zerlina.G.Wuisan@bio.uni-giessen.de.
Dorothee SchilloCentre of Molecular Biodiversity, Zoological Research Museum Alexander Koenig, 53113 Bonn, Germany. doro.schillo@gmail.com.
Robert BaraFaculty of Fisheries and Marine Science, Sam Ratulangi University, Manado 95115, Indonesia. robert.bara@unsrat.ac.id.
Fontje KaligisFaculty of Fisheries and Marine Science, Sam Ratulangi University, Manado 95115, Indonesia. fontjekaligis@yahoo.com.
Heike WägeleCentre of Molecular Biodiversity, Zoological Research Museum Alexander Koenig, 53113 Bonn, Germany. H.Waegele@leibniz-zfmk.de.
Gabriele M KönigInstitute for Pharmaceutical Biology, Rheinische Friedrich-Wilhelms-University Bonn, 53115 Bonn, Germany. g.koenig@uni-bonn.de.
Till F SchäberleInstitute for Insect Biotechnology, Justus-Liebig-University Giessen, 35392 Giessen, Germany. till.f.schaeberle@agrar.uni-giessen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The species diversity of marine heterobranch sea slugs found on field trips around Bunaken Island (North Sulawesi, Indonesia) and adjacent islands of the Bunaken National Marine Park forms the basis of this review. In a survey performed in 2015, 80 species from 23 families were collected, including 17 new species. Only three of these have been investigated previously in studies from Indonesia. Combining species diversity with a former study from 2003 reveals in total 140 species from this locality. The diversity of bioactive compounds known and yet to be discovered from these organisms is summarized and related to the producer if known or suspected (might it be down the food chain, de novo synthesised from the slug or an associated bacterium). Additionally, the collection of microorganisms for the discovery of natural products of pharmacological interest from this hotspot of biodiversity that is presented here contains more than 50 species that have never been investigated before in regard to bioactive secondary metabolites. This highlights the great potential of the sea slugs and the associated microorganisms for the discovery of natural products of pharmacological interest from this hotspot of biodiversity.

Indexed as

AnimalsBiodiversityBiological ProductsHumansIndonesiaTritonia Sea SlugBiological Productsbioactivitybiodiversitynatural productssea slug

Identifiers

PMID29215579
PMCPMC5742844

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.