Evidence map›Paper›PMID 29215551›Full record

ArticleInternational journal of molecular sciences2017

CMG2 Expression Is an Independent Prognostic Factor for Soft Tissue Sarcoma Patients.

Thomas Greither, Alice Wedler, Swetlana Rot, Jacqueline Keßler, Astrid Kehlen, Hans-Jürgen Holzhausen, Matthias Bache, Peter Würl, Helge Taubert, Matthias Kappler

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Knockdown ofJournal of Cancer · 2020
    Article
  4. Article
  5. Review
  6. Article
  7. Frontiers in medicine · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Thomas GreitherCenter for Reproductive Medicine and Andrology, Martin Luther University, 06120 Halle (Saale), Germany. thomas.greither@medizin.uni-halle.de.ORCID 0000-0002-1888-7813
Alice WedlerCenter for Reproductive Medicine and Andrology, Martin Luther University, 06120 Halle (Saale), Germany. alice.wedler@student.uni-halle.de.
Swetlana RotDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. swetlana.rot@medizin.uni-halle.de.
Jacqueline KeßlerDepartment of Radiotherapy, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. jacqueline.kessler@medizin.uni-halle.de.
Astrid KehlenInstitute of Medical Microbiology, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. astrid.kehlen@medizin.uni-halle.de.
Hans-Jürgen HolzhausenInstitute of Pathology, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. hans-juergen.holzhausen@medizin.uni-halle.de.
Matthias BacheDepartment of Radiotherapy, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. matthias.bache@medizin.uni-halle.de.
Peter WürlDepartment of General and Visceral Surgery, Hospital Dessau, 06847 Dessau-Roßlau, Germany. peter.wuerl@klinikum-dessau.de.
Helge TaubertClinic of Urology, FA University Hospital Erlangen-Nuremberg, 91054 Erlangen, Germany. Helge.Taubert@uk-erlangen.de.ORCID 0000-0002-9077-1727
Matthias KapplerDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. matthias.kappler@medizin.uni-halle.de.
Martin Luther University Halle-Wittenberg · DEStädtisches Klinikum Dessau · DEUniversitätsklinikum Erlangen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The capillary morphogenesis gene 2 (CMG2), also known as the anthrax toxin receptor 2 (ANTXR2), is a transmembrane protein putatively involved in extracellular matrix (ECM) adhesion and tissue remodeling. CMG2 promotes endothelial cell proliferation and exhibits angiogenic properties. Its downregulation is associated with a worsened survival of breast carcinoma patients. Aim of this study was to analyze the CMG2 mRNA and protein expression in soft tissue sarcoma and their association with patient outcome. CMG2 mRNA was measured in 121 tumor samples of soft tissue sarcoma patients using quantitative real-time PCR. CMG2 protein was evaluated in 52 tumor samples by ELISA. CMG2 mRNA was significantly correlated with the corresponding CMG2 protein expression (r

Indexed as

Biomarkers, TumorFemaleHumansMaleMiddle AgedReceptors, PeptideRNA, MessengerSarcomaSoft Tissue NeoplasmsSurvival AnalysisANTXR2 protein, humanBiomarkers, TumorReceptors, PeptideRNA, MessengerCMG2outcomepathobiologysoft tissue sarcoma

Identifiers

PMID29215551
PMCPMC5751250
OpenAlexW2772010447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.