ArticleScientific reports2017
Integrated DNA methylome and transcriptome analysis reveals the ethylene-induced flowering pathway genes in pineapple.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Developing pineapples with an extended shelf life through deletion of the abscisic-acid-responsive element in the enhancer sequence of the 1-aminocyclopropane-1-carboxylate synthase gene AcoACS1.Frontiers in plant science · 2026Article
- From natural induction to artificial regulation: a review on the mechanisms and techniques of flowering in pineapple.Frontiers in plant science · 2025Review
- Multi-omic analysis of the extension of broccoli quality during storage by folic acid.Journal of advanced research · 2024Article
- Comparative transcriptome analysis reveals candidate genes for cold stress response and early flowering in pineapple.Scientific reports · 2023Article
- Using landscape genomics to assess local adaptation and genomic vulnerability of a perennial herbFrontiers in genetics · 2023Article
- The genome of Aechmea fasciata provides insights into the evolution of tank epiphytic habits and ethylene-induced flowering.Communications biology · 2022Article
- Integrated analysis of DNA methylome and transcriptome reveals epigenetic regulation of CAM photosynthesis in pineapple.BMC plant biology · 2021Article
- Article
- Identification and characterization of pineapple leaf lncRNAs in crassulacean acid metabolism (CAM) photosynthesis pathway.Scientific reports · 2019Article
- The Impact of cDNA Normalization on Long-Read Sequencing of a Complex Transcriptome.Frontiers in genetics · 2019Article
- Article
- Transcriptome profiling in the spathe of Anthurium andraeanum 'Albama' and its anthocyanin-loss mutant 'Xueyu'.Scientific data · 2018Article
- Long Non-coding RNAs in Endothelial Biology.Frontiers in physiology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ethylene has long been used to promote flowering in pineapple production. Ethylene-induced flowering is dose dependent, with a critical threshold level of ethylene response factors needed to trigger flowering. The mechanism of ethylene-induced flowering is still unclear. Here, we integrated isoform sequencing (iso-seq), Illumina short-reads sequencing and whole-genome bisulfite sequencing (WGBS) to explore the early changes of transcriptomic and DNA methylation in pineapple following high-concentration ethylene (HE) and low-concentration ethylene (LE) treatment. Iso-seq produced 122,338 transcripts, including 26,893 alternative splicing isoforms, 8,090 novel transcripts and 12,536 candidate long non-coding RNAs. The WGBS results suggested a decrease in CG methylation and increase in CHH methylation following HE treatment. The LE and HE treatments induced drastic changes in transcriptome and DNA methylome, with LE inducing the initial response to flower induction and HE inducing the subsequent response. The dose-dependent induction of FLOWERING LOCUS T-like genes (FTLs) may have contributed to dose-dependent flowering induction in pineapple by ethylene. Alterations in DNA methylation, lncRNAs and multiple genes may be involved in the regulation of FTLs. Our data provided a landscape of the transcriptome and DNA methylome and revealed a candidate network that regulates flowering time in pineapple, which may promote further studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.